C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polo-like kinase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028680 Plk3 10090 - 4:117128655-117133963 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000076859 Plk3-001 117128655-117133963 protein_coding
  ENSMUST00000126135 Plk3-002 117128655-117133944 processed_transcript
  ENSMUST00000147730 Plk3-003 117128657-117133799 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000076859ENSMUST00000126135ENSMUST00000147730
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000076859 2.735±0.71 1.948±1.10 5.242±0.77 4.272±1.03 2.011±0.86 27.032±10.43 0.653±0.33 1.873±0.41 3.134±2.05 4.589±1.06 0.569±0.10 3.976±1.52 14.288±7.61 0.477±0.09
ENSMUST00000126135 0.663±0.10 0.975±0.24 N/A 0.846±0.20 0.921±0.42 3.260±0.76 0.292±0.08 0.571±0.21 1.227±0.83 2.219±0.00 0.210±0.13 1.203±0.48 1.983±1.62 0.062±0.00
ENSMUST00000147730 0.883±0.08 1.174±0.27 N/A 1.158±0.00 1.925±0.85 N/A 0.569±0.22 0.933±0.27 4.401±1.75 2.887±0.29 0.657±0.51 1.115±0.00 9.993±1.45 0.123±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093U CIL_00093U_0002 VISTA 4:117090982-117692314

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000302 IEA response to reactive oxygen species
GO:0002039 IEA p53 binding
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0005795 IEA Golgi stack
GO:0005813 IEA centrosome
GO:0006468 IEA protein phosphorylation
GO:0006970 IEA response to osmotic stress
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0009314 IEA response to radiation
GO:0030425 IEA dendrite
GO:0031122 IEA cytoplasmic microtubule organization
GO:0032465 IEA regulation of cytokinesis
GO:0043025 IEA neuronal cell body
GO:0043066 IEA negative regulation of apoptotic process
GO:0051302 IEA regulation of cell division
GO:0090166 IEA Golgi disassembly
GO:0090316 IEA positive regulation of intracellular protein transport
GO:2000777 IEA positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038754 plk3 polo-like kinase 3 (Drosophila) protein_coding Danio_rerio
ENSG00000173846 PLK3 polo-like kinase 3 protein_coding Homo_sapiens

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