C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: toll-like receptor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000308979 TLR1-201 ENSG00000174125 9606 - 4:38796257-38804791 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalLiverOvaryPlacentaTestisENST00000308979
Transcript ID Adrenal Liver Ovary Placenta Testis
ENST00000308979 2.891±0.00 0.251±0.00 1.559±0.00 1.088±0.49 0.381±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007A6 CIL_0007A6_0001 CGP 4:38790677-38856817

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002224 IEA toll-like receptor signaling pathway
GO:0002755 IEA MyD88-dependent toll-like receptor signaling pathway
GO:0004872 TAS receptor activity
GO:0004888 IEA:NAS transmembrane signaling receptor activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006952 IEA defense response
GO:0006954 IEA inflammatory response
GO:0006955 TAS:IEA immune response
GO:0007165 TAS:IEA signal transduction
GO:0016020 NAS membrane
GO:0016021 IEA integral component of membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0034130 IEA toll-like receptor 1 signaling pathway
GO:0035354 IDA Toll-like receptor 1-Toll-like receptor 2 protein complex
GO:0042116 IEA:NAS macrophage activation
GO:0042495 IEA:IDA detection of triacyl bacterial lipopeptide
GO:0042535 ISS positive regulation of tumor necrosis factor biosynthetic process
GO:0045087 IEA innate immune response
GO:0045410 ISS positive regulation of interleukin-6 biosynthetic process
GO:0046982 IDA protein heterodimerization activity
GO:0050707 IEA regulation of cytokine secretion
GO:0071727 IDA cellular response to triacyl bacterial lipopeptide

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000059349 Tlr1-201 protein_coding Mus_musculus 0 1535

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