C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: selectin P (granule membrane protein 140kDa, antigen CD62)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174175 SELP 9606 - 1:169588849-169630193 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263686 SELP-001 169588852-169630112 protein_coding
  ENST00000367786 SELP-005 169589514-169630076 protein_coding
  ENST00000367788 SELP-006 169590147-169630193 protein_coding
  ENST00000367795 SELP-008 169603026-169630086 protein_coding
  ENST00000426706 SELP-002 169588849-169619219 protein_coding
  ENST00000458599 SELP-004 169590147-169630077 protein_coding
  ENST00000466167 SELP-009 169589077-169591570 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263686ENST00000367786ENST00000367788ENST00000367795ENST00000426706ENST00000466167
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263686 4.059±0.00 14.410±0.00 0.669±0.00 N/A 1.523±0.79 2.445±0.00 1.013±0.00 0.896±0.00 N/A 7.957±0.00 N/A 1.298±0.80 2.371±0.28 2.684±0.00
ENST00000367786 N/A N/A 0.592±0.00 N/A N/A N/A N/A 0.386±0.00 N/A 0.441±0.00 N/A N/A N/A N/A
ENST00000367788 N/A N/A N/A N/A N/A 0.114±0.00 0.239±0.00 N/A 0.490±0.00 N/A N/A N/A N/A N/A
ENST00000367795 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.340±0.00 N/A 0.343±0.00
ENST00000426706 1.287±0.00 3.017±0.00 N/A 0.077±0.05 0.645±0.00 0.955±0.00 0.268±0.10 1.523±0.00 0.432±0.00 6.287±0.00 0.111±0.00 0.299±0.08 2.029±1.12 N/A
ENST00000466167 N/A N/A N/A N/A N/A 0.519±0.00 N/A N/A N/A N/A N/A 1.059±0.63 2.063±0.00 1.086±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001530 IMP lipopolysaccharide binding
GO:0001948 IEA glycoprotein binding
GO:0002576 TAS platelet degranulation
GO:0002687 IEA positive regulation of leukocyte migration
GO:0005515 IPI:IEA protein binding
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006954 IEA inflammatory response
GO:0007155 TAS cell adhesion
GO:0007157 IEA heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 IDA leukocyte cell-cell adhesion
GO:0007596 TAS blood coagulation
GO:0008201 IDA heparin binding
GO:0009897 IDA external side of plasma membrane
GO:0010572 ISS positive regulation of platelet activation
GO:0014068 IDA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IEA membrane
GO:0030168 TAS platelet activation
GO:0030246 IEA carbohydrate binding
GO:0031088 TAS platelet dense granule membrane
GO:0031092 IDA platelet alpha granule membrane
GO:0032496 IC response to lipopolysaccharide
GO:0033623 IMP regulation of integrin activation
GO:0033691 IDA sialic acid binding
GO:0042806 IDA fucose binding
GO:0043208 TAS glycosphingolipid binding
GO:0048306 IEA calcium-dependent protein binding
GO:0050829 IC defense response to Gram-negative bacterium
GO:0050900 TAS leukocyte migration
GO:0050901 IEA leukocyte tethering or rolling
GO:0070492 IDA oligosaccharide binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009123 sele selectin E protein_coding Danio_rerio
ENSDARG00000042138 selp selectin P protein_coding Danio_rerio
ENSMUSG00000026580 Selp selectin, platelet protein_coding Mus_musculus

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