C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: selectin, platelet
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026580 Selp 10090 + 1:164115264-164150026 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000160000 Selp-004 164141318-164142792 retained_intron
  ENSMUST00000161020 Selp-003 164144702-164150011 retained_intron
  ENSMUST00000161152 Selp-002 164141877-164149141 nonsense_mediated_decay
  ENSMUST00000162102 Selp-005 164146763-164149154 retained_intron
  ENSMUST00000162746 Selp-001 164115264-164150026 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartLungMuscleOvaryPlacentaENSMUST00000160000ENSMUST00000161020ENSMUST00000162746
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Lung Muscle Ovary Placenta
ENSMUST00000160000 N/A N/A N/A N/A 2.072±0.34 N/A N/A N/A 4.718±0.00 N/A
ENSMUST00000161020 N/A N/A N/A N/A N/A N/A N/A 0.120±0.00 N/A N/A
ENSMUST00000162746 2.032±0.34 0.136±0.05 2.096±0.20 1.566±0.27 0.289±0.05 0.241±0.05 1.135±0.10 0.279±0.07 0.882±0.25 0.342±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093H CIL_00093H_0002 VISTA 1:163597221-164199818

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001530 IEA lipopolysaccharide binding
GO:0001948 IDA glycoprotein binding
GO:0002687 IGI positive regulation of leukocyte migration
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006954 IMP inflammatory response
GO:0007157 IMP heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 IMP leukocyte cell-cell adhesion
GO:0008201 IEA heparin binding
GO:0009897 IDA external side of plasma membrane
GO:0010572 IMP positive regulation of platelet activation
GO:0014068 ISS positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0031092 IEA platelet alpha granule membrane
GO:0033623 ISS regulation of integrin activation
GO:0033691 IDA sialic acid binding
GO:0042806 IEA fucose binding
GO:0048306 IDA calcium-dependent protein binding
GO:0050900 IMP leukocyte migration
GO:0050901 IMP leukocyte tethering or rolling
GO:0070492 IEA oligosaccharide binding
GO:0071354 ISO cellular response to interleukin-6

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009123 sele selectin E protein_coding Danio_rerio
ENSDARG00000042138 selp selectin P protein_coding Danio_rerio
ENSG00000174175 SELP selectin P (granule membrane protein 140kDa, antigen CD62) protein_coding Homo_sapiens

Loading