C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleckstrin homology-like domain, family A, member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174307 PHLDA3 9606 - 1:201464383-201469237 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367309 PHLDA3-002 201465958-201469237 protein_coding
  ENST00000367311 PHLDA3-001 201464383-201469184 protein_coding
  ENST00000485436 PHLDA3-003 201465853-201468581 processed_transcript
  ENST00000497057 PHLDA3-004 201465944-201466657 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367309ENST00000367311ENST00000485436ENST00000497057
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367309 N/A 11.101±0.00 N/A 15.488±13.73 35.272±30.54 1.692±0.00 3.967±3.55 5.281±5.18 1.342±1.10 1.554±0.00 23.801±0.00 15.893±3.53 42.827±0.00 11.147±1.15
ENST00000367311 6.147±0.00 3.840±0.00 0.086±0.00 9.539±0.00 11.240±10.94 4.260±0.00 1.422±1.35 3.790±0.00 0.355±0.00 1.542±1.25 N/A 5.998±4.26 3.323±0.63 4.329±0.00
ENST00000485436 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.563±0.00 N/A N/A N/A
ENST00000497057 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.908±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005546 IDA phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 IDA phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0009653 TAS anatomical structure morphogenesis
GO:0010314 IDA phosphatidylinositol-5-phosphate binding
GO:0032266 IDA phosphatidylinositol-3-phosphate binding
GO:0042771 IDA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043065 IDA positive regulation of apoptotic process
GO:0043325 IDA phosphatidylinositol-3,4-bisphosphate binding
GO:0051898 IDA negative regulation of protein kinase B signaling
GO:0070062 IDA extracellular vesicular exosome
GO:0080025 IDA phosphatidylinositol-3,5-bisphosphate binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037804 phlda3 pleckstrin homology-like domain, family A, member 3 protein_coding Danio_rerio
ENSMUSG00000041801 Phlda3 pleckstrin homology-like domain, family A, member 3 protein_coding Mus_musculus

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