C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleckstrin homology-like domain, family A, member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041801 Phlda3 10090 + 1:135766119-135769136 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038945 Phlda3-001 135766119-135769136 protein_coding
  ENSMUST00000136445 Phlda3-002 135767134-135768922 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038945ENSMUST00000136445
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038945 193.272±63.50 76.704±21.52 59.530±8.08 7.230±0.82 162.764±73.29 17.700±1.41 10.440±2.95 14.164±2.51 1.881±1.38 47.070±1.65 133.408±22.89 36.139±12.91 16.117±11.32 1.635±0.94
ENSMUST00000136445 85.624±25.57 N/A N/A 2.513±0.00 101.625±3.33 N/A 6.436±1.70 7.694±0.42 0.288±0.00 37.872±0.05 N/A 7.541±0.74 5.271±0.20 0.479±0.17

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005546 ISS phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 ISS phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005737 IEA cytoplasm
GO:0005886 ISS plasma membrane
GO:0010314 ISS phosphatidylinositol-5-phosphate binding
GO:0032266 ISS phosphatidylinositol-3-phosphate binding
GO:0042771 ISS intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043065 ISS positive regulation of apoptotic process
GO:0043325 ISS phosphatidylinositol-3,4-bisphosphate binding
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0070062 IEA extracellular vesicular exosome
GO:0080025 ISS phosphatidylinositol-3,5-bisphosphate binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037804 phlda3 pleckstrin homology-like domain, family A, member 3 protein_coding Danio_rerio
ENSG00000174307 PHLDA3 pleckstrin homology-like domain, family A, member 3 protein_coding Homo_sapiens

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