C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine-like receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174600 CMKLR1 9606 - 12:108288044-108339341 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000312143 CMKLR1-001 108288044-108339317 protein_coding
  ENST00000412676 CMKLR1-201 108288044-108320662 protein_coding
  ENST00000549466 CMKLR1-004 108292533-108317917 protein_coding
  ENST00000550402 CMKLR1-002 108291671-108339341 protein_coding
  ENST00000550573 CMKLR1-003 108292522-108320662 protein_coding
  ENST00000552995 CMKLR1-005 108291570-108339313 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000312143ENST00000412676ENST00000550402ENST00000552995
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000312143 1.718±0.00 0.433±0.00 0.494±0.00 1.237±0.00 0.936±0.27 N/A 0.701±0.11 1.565±0.00 3.538±0.66 0.471±0.30 4.919±1.57 2.179±1.83
ENST00000412676 N/A N/A 0.240±0.00 N/A N/A N/A N/A N/A N/A 0.662±0.00 N/A N/A
ENST00000550402 N/A 1.264±0.00 0.102±0.00 N/A 1.610±0.00 0.413±0.00 N/A 3.387±0.00 4.042±0.00 N/A N/A N/A
ENST00000552995 N/A N/A 0.082±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001M9 CIL_0001M9_0001 CGP 12:108129471-108339341

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 TAS skeletal system development
GO:0004872 TAS receptor activity
GO:0004930 NAS:IEA G-protein coupled receptor activity
GO:0004950 IEA chemokine receptor activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006935 IEA:IDA chemotaxis
GO:0006955 TAS immune response
GO:0007186 IEA:IDA G-protein coupled receptor signaling pathway
GO:0010759 IMP positive regulation of macrophage chemotaxis
GO:0016021 IEA:NAS integral component of membrane
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0032695 ISS negative regulation of interleukin-12 production
GO:0045600 ISS positive regulation of fat cell differentiation
GO:0050848 IDA regulation of calcium-mediated signaling
GO:0070098 IEA chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090890 cmklr1 chemokine-like receptor 1 protein_coding Danio_rerio
ENSDARG00000092087 CMKLR1 (2 of 3) chemokine-like receptor 1 protein_coding Danio_rerio
ENSDARG00000093228 CMKLR1 (3 of 3) chemokine-like receptor 1 protein_coding Danio_rerio
ENSMUSG00000042190 Cmklr1 chemokine-like receptor 1 protein_coding Mus_musculus

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