C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine-like receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042190 Cmklr1 10090 - 5:113612354-113650426 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047936 Cmklr1-001 113612354-113650426 protein_coding
  ENSMUST00000132065 Cmklr1-002 113614036-113627615 protein_coding
  ENSMUST00000142854 Cmklr1-004 113614927-113643603 protein_coding
  ENSMUST00000151460 Cmklr1-003 113631306-113650396 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047936ENSMUST00000132065
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047936 24.907±15.87 3.878±2.09 2.743±0.27 0.466±0.07 13.362±6.42 1.593±0.61 1.781±0.57 1.278±0.08 0.574±0.12 27.587±12.45 0.999±0.33 4.623±1.36 4.732±3.79 9.602±2.39
ENSMUST00000132065 48.480±24.04 17.616±2.37 1.508±0.00 0.389±0.05 53.415±19.82 4.508±1.88 8.674±1.39 4.017±0.91 0.917±0.39 77.419±31.51 N/A 16.833±6.14 6.415±4.86 11.661±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001M9 CIL_0001M9_0002 CGP 5:113490333-113650426

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004950 IEA chemokine receptor activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0006935 IEA chemotaxis
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0010759 IEA positive regulation of macrophage chemotaxis
GO:0016021 IEA integral component of membrane
GO:0032088 ISS negative regulation of NF-kappaB transcription factor activity
GO:0032695 IMP negative regulation of interleukin-12 production
GO:0045600 IMP positive regulation of fat cell differentiation
GO:0050848 IEA regulation of calcium-mediated signaling
GO:0070098 IEA chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090890 cmklr1 chemokine-like receptor 1 protein_coding Danio_rerio
ENSDARG00000092087 CMKLR1 (2 of 3) chemokine-like receptor 1 protein_coding Danio_rerio
ENSDARG00000093228 CMKLR1 (3 of 3) chemokine-like receptor 1 protein_coding Danio_rerio
ENSG00000174600 CMKLR1 chemokine-like receptor 1 protein_coding Homo_sapiens

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