C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DENN/MADD domain containing 2C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175984 DENND2C 9606 - 1:114582848-114670422 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000393274 DENND2C-005 114582850-114670035 protein_coding
  ENST00000393276 DENND2C-001 114582848-114670111 protein_coding
  ENST00000393277 DENND2C-201 114582851-114626193 protein_coding
  ENST00000481894 DENND2C-002 114586736-114625325 processed_transcript
  ENST00000493549 DENND2C-004 114625698-114670422 processed_transcript
  ENST00000495031 DENND2C-003 114582851-114588557 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000393274ENST00000393276ENST00000393277ENST00000481894ENST00000495031
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000393274 N/A N/A 0.028±0.00 0.110±0.06 0.173±0.00 0.144±0.00 0.131±0.00 N/A N/A N/A 1.557±0.00 0.191±0.00 N/A N/A
ENST00000393276 0.190±0.00 N/A N/A N/A N/A 0.118±0.00 N/A 0.105±0.00 0.191±0.00 0.236±0.00 0.736±0.00 0.460±0.00 0.025±0.00 N/A
ENST00000393277 N/A N/A 0.149±0.00 0.203±0.00 0.652±0.00 0.113±0.00 N/A N/A N/A 0.166±0.00 3.001±0.00 N/A N/A N/A
ENST00000481894 0.255±0.00 0.450±0.00 0.040±0.00 0.189±0.00 N/A 0.294±0.00 0.156±0.00 0.137±0.00 N/A N/A N/A 0.192±0.03 0.083±0.00 1.459±0.00
ENST00000495031 0.377±0.00 0.726±0.00 N/A 0.357±0.00 N/A 0.246±0.00 0.609±0.00 0.452±0.00 1.011±0.00 0.680±0.00 N/A 0.374±0.14 0.069±0.04 2.449±0.41

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0017112 IDA Rab guanyl-nucleotide exchange factor activity
GO:0032851 IDA positive regulation of Rab GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073738 dennd2c DENN/MADD domain containing 2C protein_coding Danio_rerio
ENSMUSG00000007379 Dennd2c DENN/MADD domain containing 2C protein_coding Mus_musculus

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