C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DENN/MADD domain containing 2C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000007379 Dennd2c 10090 + 3:103102604-103169769 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000166143 Dennd2c-002 103102660-103157272 retained_intron
  ENSMUST00000172288 Dennd2c-001 103127556-103169738 protein_coding
  ENSMUST00000173037 Dennd2c-005 103140968-103169731 retained_intron
  ENSMUST00000173206 Dennd2c-003 103102604-103169769 protein_coding
  ENSMUST00000174060 Dennd2c-004 103140326-103168664 processed_transcript
  ENSMUST00000174486 Dennd2c-006 103149164-103158518 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000166143ENSMUST00000172288ENSMUST00000173037ENSMUST00000173206ENSMUST00000174060ENSMUST00000174486
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000166143 N/A 0.142±0.06 N/A N/A N/A 0.109±0.02 N/A N/A 0.032±0.00 N/A N/A N/A N/A N/A
ENSMUST00000172288 0.123±0.03 0.163±0.05 1.040±0.00 0.086±0.02 0.417±0.05 0.135±0.09 0.196±0.02 0.152±0.04 1.737±1.35 0.740±0.38 0.923±0.00 0.453±0.23 0.674±0.26 0.223±0.08
ENSMUST00000173037 0.207±0.10 0.057±0.00 0.931±0.02 0.134±0.02 0.783±0.26 0.133±0.01 0.098±0.02 0.140±0.00 1.415±1.21 0.747±0.43 0.217±0.05 0.339±0.10 0.314±0.02 0.378±0.00
ENSMUST00000173206 0.099±0.00 0.086±0.00 N/A 0.072±0.00 0.359±0.00 N/A 0.087±0.00 0.213±0.00 0.484±0.48 N/A N/A 0.160±0.00 0.217±0.00 0.228±0.00
ENSMUST00000174060 0.193±0.00 0.105±0.07 N/A 0.085±0.00 0.312±0.13 0.127±0.01 0.198±0.01 0.214±0.00 0.038±0.00 0.284±0.02 N/A 0.316±0.14 0.418±0.18 0.173±0.00
ENSMUST00000174486 N/A N/A N/A 0.205±0.00 0.385±0.00 0.299±0.09 N/A 0.139±0.04 0.034±0.00 N/A N/A 0.586±0.46 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006WT CIL_0006WT_0002 CGP 3:103074014-103169769
CIL_0003RY CIL_0003RY_0002 CGP 3:103102604-103179166

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005575 ND cellular_component
GO:0017112 ISS Rab guanyl-nucleotide exchange factor activity
GO:0032851 ISS positive regulation of Rab GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073738 dennd2c DENN/MADD domain containing 2C protein_coding Danio_rerio
ENSG00000175984 DENND2C DENN/MADD domain containing 2C protein_coding Homo_sapiens

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