C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BCL2-related ovarian killer
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000176720 BOK 9606 + 2:241558721-241574138 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000318407 BOK-001 241558721-241574138 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000318407
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000318407 33.006±0.00 8.154±0.00 2.211±0.00 17.008±13.69 62.229±59.45 13.732±12.64 1.317±1.07 12.995±0.51 5.122±1.96 6.176±5.02 0.175±0.00 13.412±7.89 10.582±2.21 10.465±3.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004UC CIL_0004UC_0003 CGP 2:241492674-241574138
CIL_0004U9 CIL_0004U9_0002 CGP 2:241558721-241637449

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 IBA mitochondrial outer membrane
GO:0006915 IDA apoptotic process
GO:0006919 IMP activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007420 IEA brain development
GO:0008283 IEP cell proliferation
GO:0008584 IEA male gonad development
GO:0008630 IBA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0031966 IDA mitochondrial membrane
GO:0042803 IBA protein homodimerization activity
GO:0042981 IEA regulation of apoptotic process
GO:0043065 IEA positive regulation of apoptotic process
GO:0046982 IBA protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0048709 IEA oligodendrocyte differentiation
GO:0051400 IEA BH domain binding
GO:0051402 IEA neuron apoptotic process
GO:0072332 IMP intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097192 IBA extrinsic apoptotic signaling pathway in absence of ligand
GO:1900119 IMP positive regulation of execution phase of apoptosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008807 bokb BCL2-related ovarian killer b protein_coding Danio_rerio
ENSDARG00000052129 boka BCL2-related ovarian killer a protein_coding Danio_rerio
ENSMUSG00000026278 Bok BCL2-related ovarian killer protein_coding Mus_musculus

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