C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BCL2-related ovarian killer
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026278 Bok 10090 + 1:93685660-93695764 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027499 Bok-001 93685660-93695764 protein_coding
  ENSMUST00000185685 Bok-002 93693817-93695455 processed_transcript
  ENSMUST00000188394 Bok-003 93686263-93694070 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027499ENSMUST00000185685ENSMUST00000188394
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027499 22.854±4.58 18.887±9.14 23.331±1.74 16.033±6.77 8.567±4.54 25.939±3.41 2.273±0.25 23.172±2.28 2.066±0.86 4.267±0.80 0.649±0.27 44.503±20.88 18.125±23.80 2.143±1.02
ENSMUST00000185685 9.604±0.00 N/A N/A N/A N/A N/A N/A N/A 1.571±0.13 6.579±0.00 0.801±0.00 29.846±0.00 2.454±0.00 N/A
ENSMUST00000188394 N/A N/A N/A N/A 5.665±0.00 N/A N/A N/A N/A 4.882±0.00 N/A N/A 4.536±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004UC CIL_0004UC_0004 CGP 1:93619751-93695764
CIL_0004U9 CIL_0004U9_0003 CGP 1:93685660-93754864

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005741 IBA mitochondrial outer membrane
GO:0006915 IEA apoptotic process
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007420 IEA brain development
GO:0008283 IEA cell proliferation
GO:0008584 IEA male gonad development
GO:0008630 IBA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0031966 IEA mitochondrial membrane
GO:0042803 IBA protein homodimerization activity
GO:0043065 IEA positive regulation of apoptotic process
GO:0046982 IBA protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0048709 IEA oligodendrocyte differentiation
GO:0051400 IEA BH domain binding
GO:0051402 IDA neuron apoptotic process
GO:0072332 IEA intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097192 IBA extrinsic apoptotic signaling pathway in absence of ligand
GO:1900119 IEA positive regulation of execution phase of apoptosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008807 bokb BCL2-related ovarian killer b protein_coding Danio_rerio
ENSDARG00000052129 boka BCL2-related ovarian killer a protein_coding Danio_rerio
ENSG00000176720 BOK BCL2-related ovarian killer protein_coding Homo_sapiens

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