C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SRY (sex determining region Y)-box 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000176887 SOX11 9606 + 2:5692667-5701385 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322002 SOX11-001 5692667-5701385 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000322002
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000322002 0.014±0.00 0.047±0.00 0.352±0.06 0.101±0.06 0.376±0.19 0.126±0.02 0.039±0.00 0.019±0.00 0.025±0.01 0.043±0.00 0.060±0.05 0.025±0.01 0.049±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008DV CIL_0008DV_0001 VISTA 2:5109485-5712892

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000976 ISS transcription regulatory region sequence-specific DNA binding
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001071 ISS nucleic acid binding transcription factor activity
GO:0001077 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001105 ISS RNA polymerase II transcription coactivator activity
GO:0001158 IDA enhancer sequence-specific DNA binding
GO:0001501 ISS skeletal system development
GO:0001822 IEA kidney development
GO:0001841 ISS neural tube formation
GO:0002089 ISS lens morphogenesis in camera-type eye
GO:0003151 ISS outflow tract morphogenesis
GO:0003211 ISS cardiac ventricle formation
GO:0003357 ISS noradrenergic neuron differentiation
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006412 IDA translation
GO:0008135 IDA translation factor activity, nucleic acid binding
GO:0008283 IEA cell proliferation
GO:0008284 ISS positive regulation of cell proliferation
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0014003 IEA oligodendrocyte development
GO:0014009 ISS glial cell proliferation
GO:0014032 ISS neural crest cell development
GO:0017015 IEP regulation of transforming growth factor beta receptor signaling pathway
GO:0021510 ISS spinal cord development
GO:0021782 ISS glial cell development
GO:0030182 IEP neuron differentiation
GO:0030513 ISS positive regulation of BMP signaling pathway
GO:0035332 ISS positive regulation of hippo signaling
GO:0035914 IEA skeletal muscle cell differentiation
GO:0045666 IMP positive regulation of neuron differentiation
GO:0045669 IMP positive regulation of osteoblast differentiation
GO:0045778 IMP positive regulation of ossification
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046887 ISS positive regulation of hormone secretion
GO:0048485 ISS sympathetic nervous system development
GO:0048557 ISS embryonic digestive tract morphogenesis
GO:0048704 ISS embryonic skeletal system morphogenesis
GO:0050672 IMP negative regulation of lymphocyte proliferation
GO:0050769 ISS positive regulation of neurogenesis
GO:0060022 ISS hard palate development
GO:0060023 ISS soft palate development
GO:0060174 ISS limb bud formation
GO:0060253 IMP negative regulation of glial cell proliferation
GO:0060412 ISS ventricular septum morphogenesis
GO:0060425 ISS lung morphogenesis
GO:0060548 ISS negative regulation of cell death
GO:0060563 ISS neuroepithelial cell differentiation
GO:0061029 ISS eyelid development in camera-type eye
GO:0061053 ISS somite development
GO:0061303 ISS cornea development in camera-type eye
GO:0061386 ISS closure of optic fissure
GO:0072395 IEP signal transduction involved in cell cycle checkpoint
GO:2000648 IMP positive regulation of stem cell proliferation
GO:2000678 ISS negative regulation of transcription regulatory region DNA binding
GO:2001111 ISS positive regulation of lens epithelial cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077811 sox11a SRY-box containing gene 11a protein_coding Danio_rerio
ENSDARG00000095743 sox11b SRY-box containing gene 11b protein_coding Danio_rerio
ENSMUSG00000063632 Sox11 SRY (sex determining region Y)-box 11 protein_coding Mus_musculus

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