C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ankyrin repeat and LEM domain containing 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000176915 ANKLE2 9606 - 12:132725503-132761888 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357997 ANKLE2-001 132725503-132761888 protein_coding
  ENST00000439231 ANKLE2-010 132730233-132742558 retained_intron
  ENST00000505031 ANKLE2-011 132729723-132738907 retained_intron
  ENST00000535036 ANKLE2-006 132735407-132748020 nonsense_mediated_decay
  ENST00000538591 ANKLE2-009 132734968-132743254 retained_intron
  ENST00000538766 ANKLE2-008 132727350-132735123 protein_coding
  ENST00000539605 ANKLE2-002 132725668-132761813 retained_intron
  ENST00000542282 ANKLE2-014 132726806-132732210 protein_coding
  ENST00000542374 ANKLE2-012 132727286-132735439 processed_transcript
  ENST00000542657 ANKLE2-003 132727133-132732100 protein_coding
  ENST00000545623 ANKLE2-004 132737043-132751334 retained_intron
  ENST00000546061 ANKLE2-005 132743239-132749027 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000357997ENST00000505031ENST00000538591ENST00000538766ENST00000539605ENST00000542657ENST00000545623
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000357997 11.427±0.00 9.431±0.00 2.096±0.00 4.712±2.46 8.508±4.22 6.404±1.30 4.428±2.92 7.808±4.41 3.582±0.68 9.821±4.91 8.266±6.46 15.397±7.34 9.595±0.46 36.385±3.42
ENST00000505031 N/A N/A 0.808±0.00 N/A 1.802±0.00 2.531±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000538591 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 94.524±0.00
ENST00000538766 N/A N/A N/A N/A 4.846±0.00 N/A 1.645±0.00 N/A 4.054±0.00 N/A N/A N/A N/A 65.017±0.00
ENST00000539605 N/A 1.746±0.00 N/A N/A N/A N/A N/A N/A N/A 0.886±0.00 N/A N/A N/A N/A
ENST00000542657 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.108±0.00 N/A N/A N/A
ENST00000545623 N/A N/A 2.838±0.00 N/A N/A N/A 2.715±0.00 N/A N/A N/A N/A N/A N/A 63.220±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00006L CIL_00006L_0002 CGP 12:132710819-132761888
CIL_00006K CIL_00006K_0002 CGP 12:132725503-132828858

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0005515 IPI protein binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0007067 IEA mitotic nuclear division
GO:0007084 IMP mitotic nuclear envelope reassembly
GO:0008601 TAS protein phosphatase type 2A regulator activity
GO:0016020 IDA membrane
GO:0030176 IDA integral component of endoplasmic reticulum membrane
GO:0035307 IDA positive regulation of protein dephosphorylation
GO:0042326 IDA negative regulation of phosphorylation
GO:0050790 TAS regulation of catalytic activity
GO:0051721 IDA protein phosphatase 2A binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035607 ankle2 ankyrin repeat and LEM domain containing 2 protein_coding Danio_rerio
ENSMUSG00000029501 Ankle2 ankyrin repeat and LEM domain containing 2 protein_coding Mus_musculus

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