C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: family with sequence similarity 89, member B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000176973 FAM89B 9606 + 11:65572349-65574198 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316409 FAM89B-001 65572349-65574198 protein_coding
  ENST00000449319 FAM89B-002 65572462-65574190 protein_coding
  ENST00000530349 FAM89B-004 65572528-65574192 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000316409ENST00000449319ENST00000530349
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000316409 N/A N/A 2.549±0.00 N/A 1.273±0.00 2.330±1.18 N/A N/A N/A N/A N/A 8.129±0.00 N/A
ENST00000449319 N/A N/A N/A N/A 7.901±6.75 3.530±0.00 0.930±0.00 N/A N/A N/A 8.531±9.11 11.476±0.00 N/A
ENST00000530349 17.037±0.00 31.332±0.00 13.329±0.00 23.846±0.00 33.165±0.00 10.765±0.00 21.441±0.00 6.453±3.39 24.602±24.07 27.586±23.79 37.833±0.22 15.376±5.53 9.659±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W1 CIL_0008W1_0001 VISTA 11:65187233-65790923
CIL_0003XG CIL_0003XG_0002 CGP 11:65570430-65574198
CIL_0004VX CIL_0004VX_0002 CGP 11:65572349-65592650

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001222 ISS transcription corepressor binding
GO:0005515 IEA protein binding
GO:0005737 ISS cytoplasm
GO:0030512 ISS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0060392 ISS negative regulation of SMAD protein import into nucleus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069106 fam89b family with sequence similarity 89, member B protein_coding Danio_rerio
ENSMUSG00000024939 Fam89b family with sequence similarity 89, member B protein_coding Mus_musculus

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