C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PRKC, apoptosis, WT1, regulator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177425 PAWR 9606 - 12:79574979-79691097 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000328827 PAWR-001 79584874-79691097 protein_coding
  ENST00000547016 PAWR-003 79688372-79690061 processed_transcript
  ENST00000547571 PAWR-005 79667979-79690030 processed_transcript
  ENST00000547699 PAWR-007 79592515-79597089 retained_intron
  ENST00000548075 PAWR-010 79574979-79597982 processed_transcript
  ENST00000548426 PAWR-002 79690018-79690814 protein_coding
  ENST00000549050 PAWR-011 79589792-79632162 processed_transcript
  ENST00000550006 PAWR-004 79621115-79690057 processed_transcript
  ENST00000550603 PAWR-009 79584879-79596534 protein_coding
  ENST00000551712 PAWR-006 79603668-79690080 protein_coding
  ENST00000552637 PAWR-008 79690054-79690581 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000328827ENST00000547699ENST00000548075ENST00000550006ENST00000551712
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000328827 2.050±0.00 2.240±0.00 0.604±0.21 3.864±1.06 3.832±0.94 0.947±0.00 4.218±0.00 3.669±2.66 3.701±1.65 0.175±0.00 4.514±1.75 1.501±0.49 4.099±1.61
ENST00000547699 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.228±0.00 N/A 8.148±0.00
ENST00000548075 N/A N/A N/A N/A N/A N/A 3.290±0.00 N/A N/A N/A 28.024±0.00 14.247±0.00 35.169±0.00
ENST00000550006 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 50.539±0.00
ENST00000551712 N/A 3.364±0.00 0.476±0.00 N/A N/A 0.594±0.00 N/A N/A 2.348±0.00 0.380±0.00 5.494±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002BE CIL_0002BE_0002 CGP 12:78863993-79691097
CIL_000884 CIL_000884_0001 VISTA 12:79045453-79646790
CIL_0002BD CIL_0002BD_0002 CGP 12:79574979-79935460

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0003714 TAS transcription corepressor activity
GO:0003779 ISS actin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005884 ISS actin filament
GO:0006351 IEA transcription, DNA-templated
GO:0006915 ISS apoptotic process
GO:0008285 TAS negative regulation of cell proliferation
GO:0019899 IDA enzyme binding
GO:0030889 IEA negative regulation of B cell proliferation
GO:0042094 IEA interleukin-2 biosynthetic process
GO:0042130 IEA negative regulation of T cell proliferation
GO:0042986 IEA positive regulation of amyloid precursor protein biosynthetic process
GO:0043065 NAS positive regulation of apoptotic process
GO:0043522 IPI leucine zipper domain binding
GO:0050860 IEA negative regulation of T cell receptor signaling pathway
GO:0051017 ISS actin filament bundle assembly
GO:0097190 IEA apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045486 pawr PRKC, apoptosis, WT1, regulator protein_coding Danio_rerio
ENSMUSG00000035873 Pawr PRKC, apoptosis, WT1, regulator protein_coding Mus_musculus

Loading