C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: GATA binding protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000179348 GATA2 9606 - 3:128479427-128493185 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341105 GATA2-001 128479427-128493185 protein_coding
  ENST00000430265 GATA2-003 128480146-128487916 protein_coding
  ENST00000487848 GATA2-002 128481019-128488530 protein_coding
  ENST00000489987 GATA2-005 128480146-128482078 processed_transcript
  ENST00000492608 GATA2-007 128486148-128490648 protein_coding
  ENST00000498200 GATA2-006 128487008-128493173 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000341105ENST00000430265ENST00000487848ENST00000489987
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000341105 2.918±0.00 1.709±0.00 N/A 2.399±0.00 0.535±0.26 N/A 7.565±0.00 0.570±0.51 2.389±1.73 N/A 2.185±2.83 17.550±11.00 3.909±0.51
ENST00000430265 3.562±0.00 6.450±0.00 0.120±0.00 N/A 0.578±0.00 1.833±0.00 4.937±0.00 0.079±0.00 3.947±0.00 0.814±0.40 N/A 8.811±0.00 4.081±0.00
ENST00000487848 N/A N/A N/A N/A 0.268±0.00 0.147±0.00 N/A N/A 0.526±0.00 N/A N/A N/A N/A
ENST00000489987 N/A N/A N/A 1.562±0.68 1.289±0.00 N/A N/A 0.057±0.00 N/A 0.245±0.00 0.250±0.00 15.270±1.49 3.668±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001158 IDA enhancer sequence-specific DNA binding
GO:0001655 IEA urogenital system development
GO:0001709 IEA cell fate determination
GO:0001892 IEA embryonic placenta development
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IDA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006909 IEA phagocytosis
GO:0007596 TAS blood coagulation
GO:0008134 IPI transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0021514 IEA ventral spinal cord interneuron differentiation
GO:0021533 IEA cell differentiation in hindbrain
GO:0021902 IEA commitment of neuronal cell to specific neuron type in forebrain
GO:0021954 IEA central nervous system neuron development
GO:0021983 IEA pituitary gland development
GO:0030154 IEA cell differentiation
GO:0030182 IEA neuron differentiation
GO:0035019 IEA somatic stem cell maintenance
GO:0035065 IEA regulation of histone acetylation
GO:0035854 IDA eosinophil fate commitment
GO:0042472 IEA inner ear morphogenesis
GO:0043234 IEA protein complex
GO:0043565 IEA sequence-specific DNA binding
GO:0045599 IMP negative regulation of fat cell differentiation
GO:0045638 IEA negative regulation of myeloid cell differentiation
GO:0045648 IEA positive regulation of erythrocyte differentiation
GO:0045650 IEA negative regulation of macrophage differentiation
GO:0045654 IEA positive regulation of megakaryocyte differentiation
GO:0045746 IDA negative regulation of Notch signaling pathway
GO:0045766 IDA positive regulation of angiogenesis
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048469 IEA cell maturation
GO:0048663 IEA neuron fate commitment
GO:0048873 IEA homeostasis of number of cells within a tissue
GO:0050766 ISS positive regulation of phagocytosis
GO:0060216 IEA definitive hemopoiesis
GO:0060872 IEA semicircular canal development
GO:0070345 IMP negative regulation of fat cell proliferation
GO:0070742 IPI C2H2 zinc finger domain binding
GO:0097154 IEA GABAergic neuron differentiation
GO:2000178 IDA negative regulation of neural precursor cell proliferation
GO:2000977 IEA regulation of forebrain neuron differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059327 gata2a GATA-binding protein 2a protein_coding Danio_rerio
ENSMUSG00000015053 Gata2 GATA binding protein 2 protein_coding Mus_musculus

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