C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: GATA binding protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015053 Gata2 10090 + 6:88193891-88207030 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000015197 Gata2-201 88198664-88207030 protein_coding
  ENSMUST00000170089 Gata2-202 88193891-88207030 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000015197ENSMUST00000170089
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000015197 16.328±12.28 17.010±2.44 10.913±0.07 1.212±0.73 3.018±0.62 1.080±0.32 2.770±1.39 7.158±1.28 0.795±0.66 47.434±12.01 1.713±0.64 14.021±6.13 19.662±13.08 1.225±0.00
ENSMUST00000170089 7.141±6.48 3.614±1.04 5.233±1.09 1.586±1.14 0.597±0.20 0.199±0.00 1.276±0.18 1.214±0.21 0.260±0.13 8.018±1.99 0.643±0.00 5.719±2.48 28.574±21.02 5.138±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001158 ISO enhancer sequence-specific DNA binding
GO:0001655 IMP urogenital system development
GO:0001709 IDA cell fate determination
GO:0001892 IMP embryonic placenta development
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006909 IEA phagocytosis
GO:0008134 IEA transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0021514 IMP ventral spinal cord interneuron differentiation
GO:0021533 IMP cell differentiation in hindbrain
GO:0021902 IMP commitment of neuronal cell to specific neuron type in forebrain
GO:0021954 IMP central nervous system neuron development
GO:0021983 IMP pituitary gland development
GO:0030154 IMP cell differentiation
GO:0030182 IMP neuron differentiation
GO:0035019 IMP somatic stem cell maintenance
GO:0035065 IDA regulation of histone acetylation
GO:0035854 IEA eosinophil fate commitment
GO:0042472 IMP inner ear morphogenesis
GO:0043234 IDA protein complex
GO:0045599 IMP negative regulation of fat cell differentiation
GO:0045638 IMP negative regulation of myeloid cell differentiation
GO:0045648 IDA positive regulation of erythrocyte differentiation
GO:0045650 IDA negative regulation of macrophage differentiation
GO:0045654 IDA positive regulation of megakaryocyte differentiation
GO:0045746 IEA negative regulation of Notch signaling pathway
GO:0045766 IMP positive regulation of angiogenesis
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048469 IMP cell maturation
GO:0048663 IMP neuron fate commitment
GO:0048873 IMP homeostasis of number of cells within a tissue
GO:0050766 ISS positive regulation of phagocytosis
GO:0060216 IMP definitive hemopoiesis
GO:0060872 IMP semicircular canal development
GO:0070345 IEA negative regulation of fat cell proliferation
GO:0070742 IEA C2H2 zinc finger domain binding
GO:0097154 IMP GABAergic neuron differentiation
GO:2000178 IMP negative regulation of neural precursor cell proliferation
GO:2000977 IMP regulation of forebrain neuron differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059327 gata2a GATA-binding protein 2a protein_coding Danio_rerio
ENSG00000179348 GATA2 GATA binding protein 2 protein_coding Homo_sapiens

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