C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myeloid-associated differentiation marker
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000179820 MYADM 9606 + 19:53866223-53876437 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336967 MYADM-201 53866357-53876428 protein_coding
  ENST00000391768 MYADM-003 53869439-53874619 protein_coding
  ENST00000391769 MYADM-002 53869406-53876435 protein_coding
  ENST00000391770 MYADM-001 53867883-53876437 protein_coding
  ENST00000391771 MYADM-202 53867883-53876428 protein_coding
  ENST00000414489 MYADM-007 53869765-53873969 protein_coding
  ENST00000421337 MYADM-004 53866223-53874256 protein_coding
  ENST00000439000 MYADM-006 53867883-53874307 protein_coding
  ENST00000448420 MYADM-005 53867883-53874094 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336967ENST00000391768ENST00000391770ENST00000391771ENST00000421337ENST00000448420
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336967 51.557±0.00 11.088±0.00 N/A 2.450±0.00 73.821±0.00 60.858±0.00 19.868±0.00 12.022±0.00 5.448±0.00 55.006±0.00 8.118±0.00 23.452±1.00 21.598±0.00 12.857±2.98
ENST00000391768 N/A N/A N/A 1.916±0.00 N/A 3.844±0.00 21.754±0.00 1.048±0.00 5.070±0.60 N/A N/A 27.380±24.22 45.853±0.00 22.841±0.00
ENST00000391770 N/A N/A 0.256±0.00 1.581±0.00 6.587±0.00 4.957±0.00 0.974±0.00 N/A 5.678±0.00 15.077±12.96 1.621±0.00 28.236±20.61 73.683±7.15 N/A
ENST00000391771 N/A N/A N/A N/A N/A N/A N/A 0.409±0.00 N/A N/A N/A N/A N/A N/A
ENST00000421337 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.307±0.00 N/A N/A N/A
ENST00000448420 N/A N/A 3.054±0.00 N/A 10.821±0.00 N/A 7.842±0.00 6.685±0.00 10.952±0.00 4.069±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004ML CIL_0004ML_0001 CGP 19:53793603-53876437
CIL_0004M7 CIL_0004M7_0001 CGP 19:53866223-53907652

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0001933 IMP negative regulation of protein phosphorylation
GO:0003674 ND molecular_function
GO:0005886 IMP plasma membrane
GO:0005911 IDA cell-cell junction
GO:0010629 IMP negative regulation of gene expression
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030335 IMP positive regulation of cell migration
GO:0030837 IMP negative regulation of actin filament polymerization
GO:0030864 IDA cortical actin cytoskeleton
GO:0031579 IMP membrane raft organization
GO:0034115 IDA negative regulation of heterotypic cell-cell adhesion
GO:0045121 IDA membrane raft
GO:0061028 IMP establishment of endothelial barrier
GO:0070062 IDA extracellular vesicular exosome
GO:0072661 IMP protein targeting to plasma membrane
GO:0090038 IMP negative regulation of protein kinase C signaling
GO:1900026 IMP positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038709 MYADM (1 of 2) myeloid-associated differentiation marker protein_coding Danio_rerio
ENSDARG00000086815 MYADM (2 of 2) myeloid-associated differentiation marker protein_coding Danio_rerio
ENSMUSG00000068566 Myadm myeloid-associated differentiation marker protein_coding Mus_musculus

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