C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: suppressor of cytokine signaling 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000180008 SOCS4 9606 + 14:55027230-55049488 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000339298 SOCS4-003 55027627-55049486 protein_coding
  ENST00000395472 SOCS4-001 55027230-55049488 protein_coding
  ENST00000553735 SOCS4-004 55027281-55031994 processed_transcript
  ENST00000555846 SOCS4-002 55027248-55046708 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000339298ENST00000395472ENST00000553735ENST00000555846
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000339298 N/A N/A N/A 0.739±0.00 1.458±0.00 N/A N/A N/A N/A 0.770±0.00 0.222±0.00 N/A N/A N/A
ENST00000395472 1.928±0.00 1.523±0.00 0.569±0.00 2.135±0.30 1.449±0.65 2.050±0.44 1.223±0.82 1.765±1.16 1.542±0.88 1.630±0.04 0.224±0.00 1.867±0.62 0.668±0.38 1.775±0.00
ENST00000553735 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.311±0.00 N/A N/A N/A
ENST00000555846 N/A N/A 1.973±0.00 N/A N/A 1.967±0.00 0.670±0.00 N/A 1.320±0.00 1.080±0.00 0.549±0.00 1.101±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000603 CIL_000603_0002 CGP 14:54938950-55049488
CIL_0000IA CIL_0000IA_0001 CGP 14:55027230-55070192

Gene Ontology
GO IDEvidence TypeGO Description
GO:0007175 IDA negative regulation of epidermal growth factor-activated receptor activity
GO:0016567 IEA protein ubiquitination
GO:0032436 IEA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 IEA intracellular signal transduction
GO:0040008 IEA regulation of growth

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078509 socs4 suppressor of cytokine signaling 4 protein_coding Danio_rerio
ENSMUSG00000048379 Socs4 suppressor of cytokine signaling 4 protein_coding Mus_musculus

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