C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: oxytocin receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000180914 OXTR 9606 - 3:8750408-8769628 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316793 OXTR-001 8750408-8769617 protein_coding
  ENST00000431493 OXTR-002 8768058-8769628 protein_coding
  ENST00000449615 OXTR-004 8767912-8768677 protein_coding
  ENST00000474615 OXTR-003 8768443-8769613 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverOvaryPlacentaENST00000316793
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Ovary Placenta
ENST00000316793 0.011±0.00 0.493±0.00 3.804±2.36 0.048±0.00 0.019±0.00 0.010±0.00 0.013±0.00 0.756±0.31 0.858±0.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005S5 CIL_0005S5_0001 CGP 3:8619400-8841808
CIL_0003C9 CIL_0003C9_0001 CGP 3:8733800-8841808
CIL_0003CT CIL_0003CT_0001 CGP 3:8750408-8963773

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001967 IEA suckling behavior
GO:0001975 IEA response to amphetamine
GO:0004930 IEA G-protein coupled receptor activity
GO:0004990 IEA oxytocin receptor activity
GO:0005000 IEA vasopressin receptor activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005902 IEA microvillus
GO:0005913 IEA cell-cell adherens junction
GO:0006936 TAS muscle contraction
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007507 IEA heart development
GO:0007565 IEA female pregnancy
GO:0007595 TAS lactation
GO:0007613 IEA memory
GO:0010701 IEA positive regulation of norepinephrine secretion
GO:0014070 IEA response to organic cyclic compound
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0017046 IEA peptide hormone binding
GO:0021537 IEA telencephalon development
GO:0030431 IEA sleep
GO:0032230 IEA positive regulation of synaptic transmission, GABAergic
GO:0032355 IEA response to estradiol
GO:0032570 IEA response to progesterone
GO:0034059 IEA response to anoxia
GO:0034097 IEA response to cytokine
GO:0035176 IEA social behavior
GO:0042220 IEA response to cocaine
GO:0042493 IEA response to drug
GO:0042711 IEA maternal behavior
GO:0042713 IEA sperm ejaculation
GO:0042755 IEA eating behavior
GO:0043434 IEA response to peptide hormone
GO:0044058 IEA regulation of digestive system process
GO:0045777 IEA positive regulation of blood pressure
GO:0048545 IEA response to steroid hormone
GO:0048565 IEA digestive tract development
GO:0051965 IEA positive regulation of synapse assembly
GO:0051968 IEA positive regulation of synaptic transmission, glutamatergic
GO:0060137 IEA maternal process involved in parturition
GO:0060206 IEA estrous cycle phase
GO:0060406 IEA positive regulation of penile erection
GO:0060455 IEA negative regulation of gastric acid secretion
GO:0070371 IEA ERK1 and ERK2 cascade
GO:0070474 IEA positive regulation of uterine smooth muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033956 oxtr oxytocin receptor protein_coding Danio_rerio
ENSDARG00000044175 oxtrl oxytocin receptor like protein_coding Danio_rerio
ENSMUSG00000049112 Oxtr oxytocin receptor protein_coding Mus_musculus

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