C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NLR family, pyrin domain containing 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182261 NLRP10 9606 - 11:7959424-7965426 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000328600 NLRP10-001 7959424-7963657 protein_coding
  ENST00000526590 NLRP10-002 7963299-7965426 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainPlacentaTestisENST00000328600
Transcript ID Bladder Brain Placenta Testis
ENST00000328600 0.039±0.00 0.039±0.00 0.070±0.05 0.049±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00096V CIL_00096V_0001 VISTA 11:7589795-8192277
CIL_0009BA CIL_0009BA_0001 VISTA 11:7904499-8509136
CIL_0007GR CIL_0007GR_0001 CGP 11:7938534-7965426
CIL_0008M3 CIL_0008M3_0001 VISTA 11:7953590-8554788
CIL_00046G CIL_00046G_0001 CGP 11:7959424-8001862

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002827 ISS positive regulation of T-helper 1 type immune response
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0019897 IDA extrinsic component of plasma membrane
GO:0035397 ISS helper T cell enhancement of adaptive immune response
GO:0036336 ISS dendritic cell migration
GO:0045087 IEA innate immune response
GO:0050829 IMP defense response to Gram-negative bacterium
GO:0050832 ISS defense response to fungus
GO:2000318 ISS positive regulation of T-helper 17 type immune response
GO:2000484 IMP positive regulation of interleukin-8 secretion
GO:2000778 IMP positive regulation of interleukin-6 secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000049709 Nlrp10 NLR family, pyrin domain containing 10 protein_coding Mus_musculus

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