C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NLR family, pyrin domain containing 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049709 Nlrp10 10090 - 7:108921860-108930158 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055745 Nlrp10-201 108921860-108930158 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000055745
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000055745 0.258±0.04 0.058±0.03 0.204±0.01 0.018±0.01 0.309±0.12 0.702±0.18 4.994±0.46 0.022±0.01 0.011±0.01 0.959±0.75 0.150±0.05 1.749±0.57 0.015±0.01 0.070±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00096V CIL_00096V_0002 VISTA 7:108496607-109099113
CIL_0009BA CIL_0009BA_0002 VISTA 7:108813133-109417303
CIL_0008M3 CIL_0008M3_0002 VISTA 7:108861322-109462713
CIL_0007GR CIL_0007GR_0002 CGP 7:108893461-108930158
CIL_0009BB CIL_0009BB_0002 VISTA 7:108902812-109503341
CIL_00046G CIL_00046G_0002 CGP 7:108921860-108942951

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002827 IMP positive regulation of T-helper 1 type immune response
GO:0005524 IEA ATP binding
GO:0005737 ISS cytoplasm
GO:0006952 RCA defense response
GO:0019897 ISS extrinsic component of plasma membrane
GO:0035397 IMP helper T cell enhancement of adaptive immune response
GO:0036336 IMP dendritic cell migration
GO:0045087 IEA innate immune response
GO:0050829 ISS defense response to Gram-negative bacterium
GO:0050832 IMP defense response to fungus
GO:2000318 IMP positive regulation of T-helper 17 type immune response
GO:2000484 ISS positive regulation of interleukin-8 secretion
GO:2000778 ISS positive regulation of interleukin-6 secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000182261 NLRP10 NLR family, pyrin domain containing 10 protein_coding Homo_sapiens

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