C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BCL6 corepressor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000183337 BCOR 9606 - X:40049815-40177329 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342274 BCOR-201 40051248-40177329 protein_coding
  ENST00000378444 BCOR-003 40051248-40097403 protein_coding
  ENST00000378455 BCOR-004 40051246-40177329 protein_coding
  ENST00000378463 BCOR-008 40049815-40068120 protein_coding
  ENST00000397354 BCOR-007 40051246-40097403 protein_coding
  ENST00000406200 BCOR-006 40062955-40177320 protein_coding
  ENST00000412952 BCOR-005 40077844-40146629 protein_coding
  ENST00000413905 BCOR-001 40049815-40064549 protein_coding
  ENST00000427012 BCOR-002 40051257-40063002 protein_coding
  ENST00000442018 BCOR-010 40051255-40062937 protein_coding
  ENST00000490976 BCOR-009 40071906-40077969 retained_intron
  ENST00000615339 BCOR-202 40071944-40077957 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000342274ENST00000378444ENST00000378455ENST00000397354ENST00000406200ENST00000413905ENST00000427012ENST00000442018ENST00000490976
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000342274 N/A 0.679±0.00 N/A N/A N/A N/A N/A N/A 0.552±0.00 N/A N/A N/A N/A N/A
ENST00000378444 2.477±0.00 N/A N/A 1.097±0.00 1.869±0.00 0.621±0.04 N/A N/A N/A N/A 1.414±0.94 2.324±1.22 1.340±0.00 1.848±0.35
ENST00000378455 N/A N/A 1.129±0.00 N/A 1.648±0.00 N/A 0.579±0.00 N/A 0.415±0.00 4.050±0.00 N/A 1.835±1.28 1.217±0.00 1.229±0.12
ENST00000397354 1.048±0.00 1.466±0.00 N/A 1.171±0.20 0.993±0.00 1.288±0.64 1.230±0.73 2.381±0.00 1.371±0.00 2.846±1.66 N/A 2.819±2.72 1.580±0.23 1.728±0.00
ENST00000406200 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.762±0.00 N/A N/A N/A
ENST00000413905 N/A N/A N/A N/A N/A 1.766±0.00 N/A N/A 1.048±0.00 N/A 2.381±1.28 N/A N/A N/A
ENST00000427012 N/A 2.128±0.00 N/A 1.102±0.00 0.658±0.00 1.687±0.00 N/A 3.677±0.00 0.900±0.00 N/A N/A N/A N/A N/A
ENST00000442018 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.788±0.00 2.380±0.00 3.491±1.11
ENST00000490976 N/A N/A N/A N/A N/A N/A N/A 0.484±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005QF CIL_0005QF_0001 CGP X:40049815-40606637

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000415 IMP negative regulation of histone H3-K36 methylation
GO:0003714 IDA transcription corepressor activity
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007507 IMP heart development
GO:0008134 IPI transcription factor binding
GO:0030502 IMP negative regulation of bone mineralization
GO:0031072 IDA heat shock protein binding
GO:0031519 IDA PcG protein complex
GO:0035518 IDA histone H2A monoubiquitination
GO:0042476 IMP odontogenesis
GO:0042826 IPI histone deacetylase binding
GO:0044212 IMP transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0051572 IMP negative regulation of histone H3-K4 methylation
GO:0060021 IMP palate development
GO:0065001 IMP specification of axis polarity
GO:0070171 IMP negative regulation of tooth mineralization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017798 bcor BCL6 co-repressor protein_coding Danio_rerio
ENSMUSG00000040363 Bcor BCL6 interacting corepressor protein_coding Mus_musculus

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