C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: IQ motif containing GTPase activating protein 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000361170 IQGAP3-001 ENSG00000183856 9606 - 1:156525405-156572540 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastColonLungMuscleOvaryPlacentaTestisENST00000361170
Transcript ID Bladder Breast Colon Lung Muscle Ovary Placenta Testis
ENST00000361170 0.076±0.00 0.490±0.00 0.106±0.00 0.075±0.00 0.025±0.00 3.473±4.37 1.359±0.20 0.859±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008JO CIL_0008JO_0001 VISTA 1:156202708-156805613
CIL_000850 CIL_000850_0001 VISTA 1:156360457-156965492

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0000187 IEA activation of MAPK activity
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0005099 IEA Ras GTPase activator activity
GO:0005515 IEA protein binding
GO:0005516 IPI calmodulin binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0005911 IEA cell-cell junction
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007265 IEA Ras protein signal transduction
GO:0008361 IEA regulation of cell size
GO:0010628 IEA positive regulation of gene expression
GO:0010629 IEA negative regulation of gene expression
GO:0016328 IEA lateral plasma membrane
GO:0017016 IEA Ras GTPase binding
GO:0017048 IEA Rho GTPase binding
GO:0032318 IEA regulation of Ras GTPase activity
GO:0032320 IEA positive regulation of Ras GTPase activity
GO:0033601 IEA positive regulation of mammary gland epithelial cell proliferation
GO:0070371 IEA ERK1 and ERK2 cascade
GO:0070856 IPI myosin VI light chain binding
GO:0071310 IEA cellular response to organic substance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000071812 Iqgap3-201 protein_coding Mus_musculus 0 5059
ENSMUST00000167377 Iqgap1-201 protein_coding Mus_musculus 0 355
ENSDART00000110283 iqgap1-201 protein_coding Danio_rerio 0 294

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