C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: claudin 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184113 CLDN5 9606 - 22:19523024-19527545 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000403084 CLDN5-003 19523027-19525383 protein_coding
  ENST00000406028 CLDN5-001 19523024-19527545 protein_coding
  ENST00000413119 CLDN5-002 19523052-19525423 protein_coding
  ENST00000618236 CLDN5-004 19523027-19524400 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000403084ENST00000413119ENST00000618236
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000403084 N/A N/A N/A N/A 0.240±0.00 N/A N/A N/A 0.485±0.00 N/A N/A N/A 4.629±3.05 N/A
ENST00000413119 N/A N/A N/A N/A N/A N/A 1.469±0.00 N/A 0.474±0.00 2.218±0.00 N/A 2.212±1.41 10.759±1.15 N/A
ENST00000618236 1041.590±0.00 325.837±0.00 0.717±0.00 20.951±18.03 79.649±75.77 122.136±120.73 6.626±5.51 12.155±10.95 4.162±0.36 236.492±230.45 19.660±14.82 23.967±10.30 63.460±31.33 23.489±15.40

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BW CIL_0008BW_0001 VISTA 22:19453681-20054184
CIL_00099J CIL_00099J_0001 VISTA 22:19461833-20062532
CIL_00095F CIL_00095F_0001 VISTA 22:19497462-20100487

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005923 ISS tight junction
GO:0016021 IEA integral component of membrane
GO:0016338 ISS calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
GO:0033270 IEA paranode region of axon
GO:0042552 IEA myelination
GO:0042802 ISS identical protein binding
GO:0043220 IEA Schmidt-Lanterman incisure
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014059 cldn5b claudin 5b protein_coding Danio_rerio
ENSDARG00000043716 cldn5a claudin 5a protein_coding Danio_rerio
ENSMUSG00000041378 Cldn5 claudin 5 protein_coding Mus_musculus

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