C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mediator complex subunit 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184634 MED12 9606 + X:71118556-71142454 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000333646 MED12-201 71118556-71142453 protein_coding
  ENST00000374080 MED12-002 71118723-71142447 protein_coding
  ENST00000374102 MED12-001 71118695-71142454 protein_coding
  ENST00000429213 MED12-005 71118835-71120052 protein_coding
  ENST00000444034 MED12-010 71136594-71140755 protein_coding
  ENST00000460771 MED12-009 71129183-71129862 processed_transcript
  ENST00000462984 MED12-007 71126374-71127691 processed_transcript
  ENST00000471663 MED12-006 71126261-71127386 processed_transcript
  ENST00000489199 MED12-008 71128315-71128820 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000333646ENST00000374080ENST00000374102ENST00000444034
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000333646 3.840±0.00 1.634±0.00 0.284±0.00 0.372±0.10 3.423±0.00 2.649±0.46 0.198±0.00 0.956±0.00 1.115±0.00 1.502±0.80 2.092±0.34 2.802±1.81 6.763±1.89 2.040±1.23
ENST00000374080 5.343±0.00 N/A N/A 1.453±0.42 N/A N/A 1.351±0.14 1.476±0.06 0.586±0.00 N/A N/A 4.037±3.87 N/A N/A
ENST00000374102 1.857±0.00 2.646±0.00 N/A 0.761±0.00 1.916±0.00 N/A 1.942±0.00 1.205±0.00 1.485±0.00 1.331±0.00 3.582±0.00 2.506±0.00 2.027±0.29 3.519±0.00
ENST00000444034 N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.439±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00057U CIL_00057U_0001 CGP X:71107404-71142454
CIL_00057X CIL_00057X_0001 CGP X:71118556-71171201

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001104 IDA:IEA RNA polymerase II transcription cofactor activity
GO:0001190 IEA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001843 IEA neural tube closure
GO:0003682 IEA chromatin binding
GO:0003712 IDA transcription cofactor activity
GO:0003713 IDA transcription coactivator activity
GO:0004872 IDA receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006367 IDA transcription initiation from RNA polymerase II promoter
GO:0007507 IEA heart development
GO:0008013 IEA beta-catenin binding
GO:0008022 IPI protein C-terminus binding
GO:0008134 IEA transcription factor binding
GO:0010467 TAS gene expression
GO:0014003 IEA oligodendrocyte development
GO:0014044 IEA Schwann cell development
GO:0016020 IDA membrane
GO:0016592 IEA mediator complex
GO:0019827 IEA stem cell maintenance
GO:0019904 IPI protein domain specific binding
GO:0030178 IMP negative regulation of Wnt signaling pathway
GO:0030374 NAS ligand-dependent nuclear receptor transcription coactivator activity
GO:0030518 IDA intracellular steroid hormone receptor signaling pathway
GO:0030521 IDA androgen receptor signaling pathway
GO:0042809 NAS vitamin D receptor binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046966 IDA thyroid hormone receptor binding
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060071 IEA Wnt signaling pathway, planar cell polarity pathway
GO:0090245 IEA axis elongation involved in somitogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056800 med12 mediator of RNA polymerase II transcription, subunit 12 homolog protein_coding Danio_rerio
ENSMUSG00000079487 Med12 mediator complex subunit 12 protein_coding Mus_musculus

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