C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mediator complex subunit 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374080 MED12-002 ENSG00000184634 9606 + X:71118723-71142447 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainHeartKidneyLiverOvaryENST00000374080
Transcript ID Adipose Brain Heart Kidney Liver Ovary
ENST00000374080 5.343±0.00 1.453±0.42 1.351±0.14 1.476±0.06 0.586±0.00 4.037±3.87

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00057U CIL_00057U_0001 CGP X:71107404-71142454
CIL_00057X CIL_00057X_0001 CGP X:71118556-71171201

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001104 IDA:IEA RNA polymerase II transcription cofactor activity
GO:0001190 IEA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001843 IEA neural tube closure
GO:0003682 IEA chromatin binding
GO:0003712 IDA transcription cofactor activity
GO:0003713 IDA transcription coactivator activity
GO:0004872 IDA receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006367 IDA transcription initiation from RNA polymerase II promoter
GO:0007507 IEA heart development
GO:0008013 IEA beta-catenin binding
GO:0008022 IPI protein C-terminus binding
GO:0008134 IEA transcription factor binding
GO:0010467 TAS gene expression
GO:0014003 IEA oligodendrocyte development
GO:0014044 IEA Schwann cell development
GO:0016020 IDA membrane
GO:0016592 IDA:IEA mediator complex
GO:0019827 IEA stem cell maintenance
GO:0019904 IPI protein domain specific binding
GO:0030178 IMP negative regulation of Wnt signaling pathway
GO:0030374 NAS ligand-dependent nuclear receptor transcription coactivator activity
GO:0030518 IDA intracellular steroid hormone receptor signaling pathway
GO:0030521 IDA androgen receptor signaling pathway
GO:0042809 NAS vitamin D receptor binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046966 IDA thyroid hormone receptor binding
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060071 IEA Wnt signaling pathway, planar cell polarity pathway
GO:0090245 IEA axis elongation involved in somitogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000117203 Med12-005 protein_coding Mus_musculus 0 9105
ENSMUST00000087948 Med12-001 protein_coding Mus_musculus 0 9075
ENSMUST00000117706 Med12-004 protein_coding Mus_musculus 0 7941
ENSMUST00000087956 Med12-003 protein_coding Mus_musculus 0 7860
ENSMUST00000148846 Med12-002 retained_intron Mus_musculus 0 3797
ENSMUST00000132269 Med12-008 processed_transcript Mus_musculus 0 1079
ENSMUST00000156131 Med12-006 retained_intron Mus_musculus 0 654
ENSMUST00000137664 Med12-009 processed_transcript Mus_musculus 0 584
ENSMUST00000146877 Med12-007 processed_transcript Mus_musculus 0 414

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