C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: formin-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184922 FMNL1 9606 + 17:45221444-45247320 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000328118 FMNL1-201 45222077-45246959 protein_coding
  ENST00000331495 FMNL1-001 45221789-45247320 protein_coding
  ENST00000585852 FMNL1-003 45230669-45234687 retained_intron
  ENST00000586092 FMNL1-011 45245326-45246475 protein_coding
  ENST00000586643 FMNL1-007 45243118-45246604 protein_coding
  ENST00000587489 FMNL1-006 45241075-45247318 protein_coding
  ENST00000587856 FMNL1-005 45233884-45247319 retained_intron
  ENST00000589911 FMNL1-010 45245324-45246553 protein_coding
  ENST00000591434 FMNL1-008 45234080-45236594 retained_intron
  ENST00000592006 FMNL1-013 45231427-45239054 processed_transcript
  ENST00000592415 FMNL1-012 45221444-45222097 processed_transcript
  ENST00000592527 FMNL1-004 45232862-45233953 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaENST00000331495ENST00000586643ENST00000587489
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENST00000331495 3.144±0.00 13.161±0.00 2.373±1.19 4.937±0.00 1.001±0.00 0.205±0.00 N/A N/A 8.192±4.85 4.201±1.70 3.092±0.90
ENST00000586643 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.397±0.00
ENST00000587489 5.182±0.00 28.968±0.00 6.304±0.00 9.059±0.00 4.939±0.00 N/A 0.767±0.00 1.380±0.00 22.426±0.00 5.775±0.38 6.468±0.84

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002QX CIL_0002QX_0001 CGP 17:45160700-45247320

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0003779 IEA actin binding
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005522 IEA profilin binding
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0006929 IEA substrate-dependent cell migration
GO:0007010 IEA cytoskeleton organization
GO:0008360 IMP regulation of cell shape
GO:0009987 IEA cellular process
GO:0016020 IDA membrane
GO:0016043 IEA cellular component organization
GO:0017048 IEA Rho GTPase binding
GO:0030036 IEA actin cytoskeleton organization
GO:0030866 IMP cortical actin cytoskeleton organization
GO:0032794 IDA GTPase activating protein binding
GO:0042995 IEA cell projection
GO:0045335 ISS phagocytic vesicle
GO:0048365 ISS Rac GTPase binding
GO:0051014 ISS actin filament severing
GO:0051015 ISS actin filament binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055713 fmnl1a formin-like 1a protein_coding Danio_rerio
ENSDARG00000075519 FMNL1 (2 of 2) formin-like 1 protein_coding Danio_rerio
ENSMUSG00000055805 Fmnl1 formin-like 1 protein_coding Mus_musculus

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