C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: coagulation factor VIII, procoagulant component
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185010 F8 9606 - X:154835788-155026940 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330287 F8-003 154835788-154886317 protein_coding
  ENST00000360256 F8-001 154835795-155022753 protein_coding
  ENST00000423959 F8-004 154984701-155026940 protein_coding
  ENST00000453950 F8-005 154993025-155026868 protein_coding
  ENST00000483822 F8-002 154965772-154966516 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000330287ENST00000360256
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000330287 6.347±0.00 16.909±0.00 N/A 4.805±2.00 6.837±0.00 7.223±0.00 N/A 6.892±0.00 5.058±0.00 11.711±0.00 N/A 5.675±0.00 10.398±0.00
ENST00000360256 4.953±0.00 4.131±0.00 1.355±0.00 N/A 2.386±0.00 2.096±0.71 8.495±1.84 3.984±0.00 2.287±0.65 1.727±0.00 2.662±0.40 1.638±0.43 3.478±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002576 TAS platelet degranulation
GO:0004252 IEA serine-type endopeptidase activity
GO:0005507 IEA copper ion binding
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0005615 IEA extracellular space
GO:0005886 TAS plasma membrane
GO:0006508 IEA proteolysis
GO:0006953 IEA acute-phase response
GO:0007155 IEA cell adhesion
GO:0007596 TAS blood coagulation
GO:0007597 TAS blood coagulation, intrinsic pathway
GO:0016491 IEA oxidoreductase activity
GO:0030168 TAS platelet activation
GO:0031093 TAS platelet alpha granule lumen
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015247 f8 coagulation factor VIII, procoagulant component protein_coding Danio_rerio
ENSMUSG00000031196 F8 coagulation factor VIII protein_coding Mus_musculus

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