C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: coagulation factor VIII
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031196 F8 10090 - X:75172715-75382615 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033539 F8-001 75172715-75382316 protein_coding
  ENSMUST00000114085 F8-201 75172719-75380041 protein_coding
  ENSMUST00000147349 F8-002 75338282-75382615 protein_coding
  ENSMUST00000151772 F8-003 75354136-75382291 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033539ENSMUST00000114085ENSMUST00000147349ENSMUST00000151772
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033539 0.103±0.01 0.194±0.11 0.036±0.01 0.039±0.01 N/A 0.050±0.00 0.065±0.03 N/A 0.034±0.00 0.025±0.00 0.014±0.00 0.204±0.08 0.022±0.01 0.037±0.01
ENSMUST00000114085 0.218±0.07 0.310±0.11 0.219±0.03 0.120±0.02 0.389±0.14 0.035±0.01 0.075±0.01 0.283±0.08 0.322±0.09 0.096±0.04 0.075±0.02 0.231±0.15 0.041±0.03 0.038±0.01
ENSMUST00000147349 N/A N/A N/A N/A N/A N/A 0.326±0.00 N/A N/A 0.169±0.00 N/A 0.435±0.00 N/A 0.139±0.00
ENSMUST00000151772 0.727±0.00 0.579±0.16 N/A N/A N/A 0.321±0.17 N/A N/A N/A 0.196±0.03 N/A 0.967±0.52 0.145±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004252 IEA serine-type endopeptidase activity
GO:0005507 IEA copper ion binding
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0006508 IEA proteolysis
GO:0006953 IEA acute-phase response
GO:0007155 IEA cell adhesion
GO:0007596 IEA blood coagulation
GO:0007597 IEA blood coagulation, intrinsic pathway
GO:0016491 IEA oxidoreductase activity
GO:0030168 IEA platelet activation
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015247 f8 coagulation factor VIII, procoagulant component protein_coding Danio_rerio
ENSG00000185010 F8 coagulation factor VIII, procoagulant component protein_coding Homo_sapiens

Loading