C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium and integrin binding 1 (calmyrin)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185043 CIB1 9606 - 15:90229975-90234047 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000328649 CIB1-001 90229975-90234047 protein_coding
  ENST00000612800 CIB1-201 90230246-90234047 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000328649ENST00000612800
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000328649 5.009±0.00 6.900±0.00 N/A 2.491±0.33 1.236±0.00 1.473±0.00 4.844±3.97 1.717±0.00 6.923±5.27 10.189±7.69 4.760±1.92 12.636±10.38 16.995±5.80 10.740±0.00
ENST00000612800 29.627±0.00 51.960±0.00 3.063±0.00 21.182±0.00 36.405±0.00 23.199±16.51 26.256±0.00 117.888±0.00 30.851±29.96 108.234±0.00 18.910±0.00 24.402±11.52 40.562±32.26 154.106±103.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008FE CIL_0008FE_0001 VISTA 15:90100149-90701385
CIL_0000SV CIL_0000SV_0001 CGP 15:90160604-90234047
CIL_0000SU CIL_0000SU_0001 CGP 15:90229975-90245811

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001933 ISS negative regulation of protein phosphorylation
GO:0001934 ISS positive regulation of protein phosphorylation
GO:0001954 ISS positive regulation of cell-matrix adhesion
GO:0002931 ISS response to ischemia
GO:0005509 IMP:IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IMP nucleoplasm
GO:0005737 IMP cytoplasm
GO:0005783 IMP endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005813 IDA centrosome
GO:0005886 IDA plasma membrane
GO:0006302 TAS double-strand break repair
GO:0006915 IMP apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007026 IDA negative regulation of microtubule depolymerization
GO:0007113 IDA endomitotic cell cycle
GO:0007155 IEA cell adhesion
GO:0007286 ISS spermatid development
GO:0008284 ISS positive regulation of cell proliferation
GO:0008285 IMP negative regulation of cell proliferation
GO:0010977 IDA negative regulation of neuron projection development
GO:0016020 IDA membrane
GO:0017016 IPI Ras GTPase binding
GO:0030027 IDA lamellipodium
GO:0030220 ISS platelet formation
GO:0030307 ISS positive regulation of cell growth
GO:0030335 ISS positive regulation of cell migration
GO:0030426 IDA growth cone
GO:0031122 IMP cytoplasmic microtubule organization
GO:0031982 IDA vesicle
GO:0032433 IDA filopodium tip
GO:0033630 IDA positive regulation of cell adhesion mediated by integrin
GO:0038163 ISS thrombopoietin-mediated signaling pathway
GO:0042127 IMP regulation of cell proliferation
GO:0042383 IDA sarcolemma
GO:0043005 IDA neuron projection
GO:0043025 IDA neuronal cell body
GO:0043066 IMP negative regulation of apoptotic process
GO:0043495 IGI protein anchor
GO:0044325 IEA ion channel binding
GO:0045653 ISS negative regulation of megakaryocyte differentiation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048554 ISS positive regulation of metalloenzyme activity
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051301 IEA cell division
GO:0051302 IMP regulation of cell division
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0070062 IDA extracellular vesicular exosome
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0070886 IDA positive regulation of calcineurin-NFAT signaling cascade
GO:0071356 IMP cellular response to tumor necrosis factor
GO:0071363 ISS cellular response to growth factor stimulus
GO:0071902 ISS positive regulation of protein serine/threonine kinase activity
GO:0071944 IDA cell periphery
GO:0090004 IGI positive regulation of establishment of protein localization to plasma membrane
GO:0090050 ISS positive regulation of cell migration involved in sprouting angiogenesis
GO:0090314 IMP positive regulation of protein targeting to membrane
GO:0097191 TAS extrinsic apoptotic signaling pathway
GO:1900026 IDA positive regulation of substrate adhesion-dependent cell spreading
GO:1901313 ISS positive regulation of gene expression involved in extracellular matrix organization
GO:1990090 IDA cellular response to nerve growth factor stimulus
GO:2000256 ISS positive regulation of male germ cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045381 cib1 calcium and integrin binding 1 (calmyrin) protein_coding Danio_rerio
ENSMUSG00000030538 Cib1 calcium and integrin binding 1 (calmyrin) protein_coding Mus_musculus

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