C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium and integrin binding 1 (calmyrin)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030538 Cib1 10090 - 7:80227156-80232813 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000065163 Cib1-001 80227156-80232813 protein_coding
  ENSMUST00000071457 Cib1-002 80227157-80232619 protein_coding
  ENSMUST00000123279 Cib1-005 80227994-80232495 protein_coding
  ENSMUST00000131402 Cib1-004 80228158-80232597 processed_transcript
  ENSMUST00000144295 Cib1-003 80231451-80232731 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000065163ENSMUST00000071457ENSMUST00000123279ENSMUST00000131402
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000065163 33.545±2.49 50.606±6.21 34.096±6.84 7.007±3.15 36.442±10.13 165.995±9.75 8.054±3.09 109.686±7.61 37.510±6.43 36.046±1.17 2.795±1.12 25.515±9.10 26.859±16.23 101.441±44.49
ENSMUST00000071457 N/A N/A N/A N/A 17.904±0.00 N/A 2.845±0.07 N/A N/A N/A 0.805±0.00 21.146±2.58 32.177±12.98 N/A
ENSMUST00000123279 N/A N/A N/A 20.611±0.00 17.481±0.00 N/A N/A N/A N/A N/A 1.423±0.00 52.345±0.00 150.439±25.04 74.068±46.75
ENSMUST00000131402 21.451±1.62 N/A N/A N/A 20.809±2.14 N/A 3.642±0.89 N/A N/A N/A 1.374±0.23 14.289±1.56 33.291±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008AY CIL_0008AY_0002 VISTA 7:80145068-80746500
CIL_0000SV CIL_0000SV_0002 CGP 7:80186841-80232813
CIL_0000SU CIL_0000SU_0002 CGP 7:80227156-80241006

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001933 IMP negative regulation of protein phosphorylation
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0001954 IMP positive regulation of cell-matrix adhesion
GO:0002931 IDA response to ischemia
GO:0005509 ISS calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005654 ISS nucleoplasm
GO:0005737 IMP cytoplasm
GO:0005783 ISS endoplasmic reticulum
GO:0005813 ISS centrosome
GO:0005886 ISS plasma membrane
GO:0006915 ISS apoptotic process
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0007026 ISS negative regulation of microtubule depolymerization
GO:0007113 ISS endomitotic cell cycle
GO:0007155 IEA cell adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007286 IMP spermatid development
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 ISS negative regulation of cell proliferation
GO:0010977 ISS negative regulation of neuron projection development
GO:0016020 IDA membrane
GO:0017016 IEA Ras GTPase binding
GO:0030027 ISS lamellipodium
GO:0030220 IMP platelet formation
GO:0030307 IMP positive regulation of cell growth
GO:0030335 IMP positive regulation of cell migration
GO:0030426 ISS growth cone
GO:0031122 ISS cytoplasmic microtubule organization
GO:0031982 IEA vesicle
GO:0032433 ISS filopodium tip
GO:0033630 ISS positive regulation of cell adhesion mediated by integrin
GO:0038163 IMP thrombopoietin-mediated signaling pathway
GO:0042127 ISS regulation of cell proliferation
GO:0042383 IDA sarcolemma
GO:0043005 ISS neuron projection
GO:0043025 ISS neuronal cell body
GO:0043066 IMP negative regulation of apoptotic process
GO:0043495 IMP protein anchor
GO:0044325 IPI ion channel binding
GO:0045653 IMP negative regulation of megakaryocyte differentiation
GO:0048471 ISS perinuclear region of cytoplasm
GO:0048554 IMP positive regulation of metalloenzyme activity
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0051301 IEA cell division
GO:0051302 ISS regulation of cell division
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0070062 IEA extracellular vesicular exosome
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0070886 IMP positive regulation of calcineurin-NFAT signaling cascade
GO:0071356 ISS cellular response to tumor necrosis factor
GO:0071363 IDA cellular response to growth factor stimulus
GO:0071902 IMP positive regulation of protein serine/threonine kinase activity
GO:0071944 ISS cell periphery
GO:0090004 IMP positive regulation of establishment of protein localization to plasma membrane
GO:0090050 IMP positive regulation of cell migration involved in sprouting angiogenesis
GO:0090314 ISS positive regulation of protein targeting to membrane
GO:1900026 ISS positive regulation of substrate adhesion-dependent cell spreading
GO:1901313 IMP positive regulation of gene expression involved in extracellular matrix organization
GO:1990090 ISS cellular response to nerve growth factor stimulus
GO:2000256 IMP positive regulation of male germ cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045381 cib1 calcium and integrin binding 1 (calmyrin) protein_coding Danio_rerio
ENSG00000185043 CIB1 calcium and integrin binding 1 (calmyrin) protein_coding Homo_sapiens

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