C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neurotrophin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185652 NTF3 9606 + 12:5432112-5521536 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331010 NTF3-002 5494132-5495159 protein_coding
  ENST00000423158 NTF3-001 5432113-5495299 protein_coding
  ENST00000535299 NTF3-003 5432112-5521536 processed_transcript
  ENST00000541234 NTF3-005 5511657-5513393 processed_transcript
  ENST00000543548 NTF3-006 5433125-5494501 processed_transcript
  ENST00000544836 NTF3-004 5511609-5513076 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000331010ENST00000423158ENST00000535299ENST00000543548
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000331010 0.143±0.00 N/A N/A N/A 0.195±0.01 N/A 0.213±0.00 N/A N/A 2.006±0.00 N/A 0.965±0.22 0.746±0.27 0.668±0.37
ENST00000423158 0.255±0.00 2.017±0.00 0.590±0.00 0.136±0.00 0.267±0.07 1.251±0.00 0.188±0.00 1.145±0.47 0.715±0.15 0.456±0.00 0.360±0.00 1.936±1.40 0.455±0.25 1.719±0.95
ENST00000535299 0.102±0.00 N/A 0.140±0.00 N/A N/A N/A 0.160±0.00 N/A 0.162±0.00 N/A N/A N/A N/A 0.187±0.00
ENST00000543548 0.199±0.00 N/A N/A N/A N/A N/A 0.272±0.00 N/A 0.648±0.00 N/A N/A 1.588±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IDA activation of MAPK activity
GO:0002092 IDA positive regulation of receptor internalization
GO:0005102 TAS:IEA receptor binding
GO:0005165 IEA neurotrophin receptor binding
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0007165 TAS signal transduction
GO:0007169 IDA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007274 IEA neuromuscular synaptic transmission
GO:0007399 TAS nervous system development
GO:0007403 IEA glial cell fate determination
GO:0007411 IEA axon guidance
GO:0007420 IEA brain development
GO:0007422 IEA peripheral nervous system development
GO:0008083 IDA growth factor activity
GO:0008284 IDA positive regulation of cell proliferation
GO:0008544 IEA epidermis development
GO:0016023 IEA cytoplasmic membrane-bounded vesicle
GO:0021675 IEA nerve development
GO:0030335 IDA positive regulation of cell migration
GO:0032148 IDA activation of protein kinase B activity
GO:0032856 IDA activation of Ras GTPase activity
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0042056 IDA chemoattractant activity
GO:0042490 IEA mechanoreceptor differentiation
GO:0042552 IEA myelination
GO:0043523 IEA regulation of neuron apoptotic process
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045687 IEA positive regulation of glial cell differentiation
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048406 IEA nerve growth factor binding
GO:0048484 IEA enteric nervous system development
GO:0048666 IEA neuron development
GO:0048699 IEA generation of neurons
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050732 IDA negative regulation of peptidyl-tyrosine phosphorylation
GO:0050804 IEA regulation of synaptic transmission
GO:0050918 IDA positive chemotaxis
GO:0050930 IDA induction of positive chemotaxis
GO:0051145 IEA smooth muscle cell differentiation
GO:2000251 IDA positive regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059043 ntf3 neurotrophin 3 protein_coding Danio_rerio
ENSMUSG00000049107 Ntf3 neurotrophin 3 protein_coding Mus_musculus

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