C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon-induced protein with tetratricopeptide repeats 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185745 IFIT1 9606 + 10:89392546-89406486 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371804 IFIT1-001 89392546-89403988 protein_coding
  ENST00000546318 IFIT1-201 89392546-89406486 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371804ENST00000546318
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371804 1.731±0.00 2.863±0.00 1.837±0.00 4.751±2.76 5.349±0.45 5.046±3.04 4.985±2.77 5.892±0.74 2.406±0.87 7.155±0.00 1.242±0.11 3.801±1.40 7.730±1.65 2.925±0.01
ENST00000546318 0.083±0.00 N/A N/A 0.521±0.00 N/A 0.369±0.00 0.423±0.00 N/A N/A N/A N/A 0.227±0.04 N/A 0.322±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001IW CIL_0001IW_0001 CGP 10:89205629-89414557
CIL_0001IT CIL_0001IT_0001 CGP 10:89213569-89414557
CIL_0007BE CIL_0007BE_0008 CGP 10:89378056-89406486
CIL_0007BE CIL_0007BE_0007 CGP 10:89392546-89421001

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 IDA RNA binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0009615 IDA response to virus
GO:0019060 IDA intracellular transport of viral protein in host cell
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0032091 IDA negative regulation of protein binding
GO:0045070 IDA positive regulation of viral genome replication
GO:0045071 IMP negative regulation of viral genome replication
GO:0050689 IDA negative regulation of defense response to virus by host
GO:0051097 IDA negative regulation of helicase activity
GO:0051607 IEA defense response to virus
GO:0060337 TAS type I interferon signaling pathway
GO:0071357 IDA cellular response to type I interferon
GO:0071360 IDA cellular response to exogenous dsRNA

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007467 si:dkey-26g8.11 si:dkey-26g8.11 protein_coding Danio_rerio
ENSDARG00000043584 ifit2 interferon-induced protein with tetratricopeptide repeats 2 protein_coding Danio_rerio
ENSDARG00000056976 si:ch211-240h7.2 si:ch211-240h7.2 protein_coding Danio_rerio
ENSDARG00000057173 zgc:123282 zgc:123282 protein_coding Danio_rerio
ENSDARG00000071012 si:dkey-116m16.3 si:dkey-116m16.3 protein_coding Danio_rerio
ENSDARG00000088069 CR759879.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000090537 si:dkey-26g8.10 si:dkey-26g8.10 protein_coding Danio_rerio
ENSDARG00000090977 ifit5 interferon-induced protein with tetratricopeptide repeats 5 protein_coding Danio_rerio

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