C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185883 ATP6V0C 9606 + 16:2513726-2520223 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330398 ATP6V0C-001 2513870-2520218 protein_coding
  ENST00000564973 ATP6V0C-005 2518999-2520218 protein_coding
  ENST00000565223 ATP6V0C-004 2514294-2519920 protein_coding
  ENST00000568562 ATP6V0C-003 2513976-2519679 protein_coding
  ENST00000618152 ATP6V0C-201 2513726-2520223 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330398ENST00000565223ENST00000568562ENST00000618152
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330398 N/A N/A 9.109±0.00 N/A 25.278±23.02 N/A 51.640±0.00 4.162±0.00 N/A 29.163±28.01 69.143±66.69 102.010±22.32 N/A
ENST00000565223 112.859±0.00 123.537±0.00 112.280±97.88 121.570±0.00 113.885±0.00 1.398±0.00 N/A N/A N/A N/A 154.030±80.25 144.141±88.38 154.670±6.66
ENST00000568562 79.205±0.00 107.352±0.00 N/A 121.775±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000618152 59.865±0.00 56.281±0.00 148.036±138.97 51.613±0.00 38.956±0.00 81.078±0.00 112.797±0.00 92.159±0.00 221.627±0.00 80.553±76.28 52.799±2.40 81.810±14.58 84.886±16.70

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000299 CIL_000299_0002 CGP 16:2496032-2520223

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005765 IDA lysosomal membrane
GO:0005925 IDA focal adhesion
GO:0006879 TAS cellular iron ion homeostasis
GO:0008286 TAS insulin receptor signaling pathway
GO:0010008 TAS endosome membrane
GO:0015078 IEA hydrogen ion transmembrane transporter activity
GO:0015991 IEA ATP hydrolysis coupled proton transport
GO:0015992 TAS proton transport
GO:0016021 IEA integral component of membrane
GO:0016032 IEA viral process
GO:0030177 IMP positive regulation of Wnt signaling pathway
GO:0030670 TAS phagocytic vesicle membrane
GO:0031625 IPI ubiquitin protein ligase binding
GO:0033177 IEA proton-transporting two-sector ATPase complex, proton-transporting domain
GO:0033179 IEA proton-transporting V-type ATPase, V0 domain
GO:0033572 TAS transferrin transport
GO:0046933 TAS proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 TAS proton-transporting ATPase activity, rotational mechanism
GO:0051701 TAS interaction with host
GO:0055085 TAS transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0090382 TAS phagosome maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036577 atp6v0cb ATPase, H+ transporting, lysosomal, V0 subunit c, b protein_coding Danio_rerio
ENSDARG00000057853 atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a protein_coding Danio_rerio
ENSMUSG00000024121 Atp6v0c ATPase, H+ transporting, lysosomal V0 subunit C protein_coding Mus_musculus

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