C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 4, subfamily F, polypeptide 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000186204 CYP4F12 9606 + 19:15672757-15697174 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000324632 CYP4F12-006 15673478-15697145 protein_coding
  ENST00000430608 CYP4F12-002 15673076-15681142 retained_intron
  ENST00000451750 CYP4F12-003 15673076-15680944 retained_intron
  ENST00000517734 CYP4F12-004 15673090-15697143 nonsense_mediated_decay
  ENST00000518629 CYP4F12-005 15673082-15697148 retained_intron
  ENST00000546608 CYP4F12-008 15681501-15697143 retained_intron
  ENST00000546792 CYP4F12-016 15673088-15680707 retained_intron
  ENST00000547332 CYP4F12-009 15673018-15682447 nonsense_mediated_decay
  ENST00000547471 CYP4F12-010 15673046-15680586 retained_intron
  ENST00000548237 CYP4F12-012 15673076-15682435 nonsense_mediated_decay
  ENST00000548435 CYP4F12-015 15673087-15681127 nonsense_mediated_decay
  ENST00000548501 CYP4F12-013 15673087-15680524 retained_intron
  ENST00000549622 CYP4F12-014 15673087-15680662 retained_intron
  ENST00000550264 CYP4F12-017 15673090-15678565 retained_intron
  ENST00000550308 CYP4F12-001 15672757-15697174 protein_coding
  ENST00000550627 CYP4F12-007 15681437-15697143 retained_intron
  ENST00000551607 CYP4F12-018 15673112-15680252 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000324632ENST00000430608ENST00000517734ENST00000518629ENST00000546608ENST00000547332ENST00000547471ENST00000548435ENST00000548501ENST00000550627
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000324632 0.926±0.00 N/A N/A 0.601±0.00 1.404±0.00 0.747±0.00 0.404±0.00 10.139±0.00 7.508±0.00 0.917±0.00 0.081±0.00 1.336±0.38 0.359±0.17 N/A
ENST00000430608 N/A 0.460±0.00 N/A 0.199±0.00 0.592±0.00 3.204±0.00 0.191±0.00 N/A N/A 1.370±0.00 N/A N/A N/A N/A
ENST00000517734 N/A N/A N/A N/A N/A N/A 0.026±0.00 1.015±0.77 N/A N/A N/A 0.665±0.47 0.041±0.01 N/A
ENST00000518629 0.568±0.00 0.755±0.00 0.265±0.00 N/A N/A 0.343±0.00 N/A 1.034±0.00 N/A N/A N/A 2.172±0.00 0.046±0.00 N/A
ENST00000546608 N/A N/A 0.307±0.00 0.129±0.00 0.282±0.00 0.965±0.00 N/A 0.177±0.00 N/A 0.135±0.00 N/A 0.167±0.00 0.031±0.00 0.171±0.10
ENST00000547332 N/A N/A N/A N/A 1.057±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000547471 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.040±0.00 0.187±0.00 N/A
ENST00000548435 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.133±0.00 N/A
ENST00000548501 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.713±0.00
ENST00000550627 N/A N/A N/A N/A N/A 1.123±0.65 N/A N/A N/A N/A N/A 0.390±0.11 N/A 0.356±0.21

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000038 ISS very long-chain fatty acid metabolic process
GO:0001676 ISS long-chain fatty acid metabolic process
GO:0003091 ISS renal water homeostasis
GO:0003095 ISS pressure natriuresis
GO:0005506 IEA iron ion binding
GO:0005737 ISS cytoplasm
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006805 TAS xenobiotic metabolic process
GO:0008392 ISS arachidonic acid epoxygenase activity
GO:0016021 IEA integral component of membrane
GO:0016324 ISS apical plasma membrane
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0017144 ISS drug metabolic process
GO:0018685 ISS alkane 1-monooxygenase activity
GO:0019369 ISS arachidonic acid metabolic process
GO:0019373 ISS epoxygenase P450 pathway
GO:0020037 IEA heme binding
GO:0030195 ISS negative regulation of blood coagulation
GO:0036101 ISS leukotriene B4 catabolic process
GO:0042360 ISS vitamin E metabolic process
GO:0042371 ISS vitamin K biosynthetic process
GO:0043231 ISS intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0047057 ISS vitamin-K-epoxide reductase (warfarin-sensitive) activity
GO:0050051 ISS leukotriene-B4 20-monooxygenase activity
GO:0055078 ISS sodium ion homeostasis
GO:0055114 IEA oxidation-reduction process
GO:0070330 IEA aromatase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000003484 Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 protein_coding Mus_musculus

Loading