C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulin induced gene 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000186480 INSIG1 9606 + 7:155297776-155310235 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000340368 INSIG1-001 155297776-155310235 protein_coding
  ENST00000342407 INSIG1-003 155297889-155308757 protein_coding
  ENST00000344756 INSIG1-201 155297776-155310233 protein_coding
  ENST00000425172 INSIG1-002 155297829-155298655 protein_coding
  ENST00000468307 INSIG1-004 155301607-155303018 retained_intron
  ENST00000476756 INSIG1-005 155298561-155308960 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000340368ENST00000342407ENST00000344756ENST00000476756
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000340368 17.083±0.00 13.680±0.00 2.056±0.00 21.028±11.90 21.634±16.67 5.896±2.27 2.593±1.34 32.270±23.64 25.720±19.47 30.928±25.87 1.678±0.72 16.497±15.71 13.623±4.95 15.580±9.23
ENST00000342407 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.915±0.00 7.607±0.00 6.601±0.00
ENST00000344756 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.001±0.00 N/A N/A
ENST00000476756 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.583±0.00 10.965±0.00 15.442±0.00 12.259±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00026E CIL_00026E_0001 CGP 7:155070324-155310235
CIL_0008KT CIL_0008KT_0001 VISTA 7:155171352-155773114

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006641 IEA triglyceride metabolic process
GO:0006695 IEA cholesterol biosynthetic process
GO:0006991 IEA response to sterol depletion
GO:0008152 TAS metabolic process
GO:0008203 IEA cholesterol metabolic process
GO:0008283 TAS cell proliferation
GO:0010894 IEA negative regulation of steroid biosynthetic process
GO:0016021 IEA integral component of membrane
GO:0016126 IEA sterol biosynthetic process
GO:0032933 IDA SREBP signaling pathway
GO:0032937 IDA SREBP-SCAP-Insig complex
GO:0042472 IEA inner ear morphogenesis
GO:0042474 IEA middle ear morphogenesis
GO:0044281 TAS small molecule metabolic process
GO:0045599 IEA negative regulation of fat cell differentiation
GO:0045717 IEA negative regulation of fatty acid biosynthetic process
GO:0060021 IEA palate development
GO:0060363 IEA cranial suture morphogenesis
GO:1901303 IMP negative regulation of cargo loading into COPII-coated vesicle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010658 insig1 insulin induced gene 1 protein_coding Danio_rerio
ENSMUSG00000045294 Insig1 insulin induced gene 1 protein_coding Mus_musculus

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