C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon, alpha 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000188379 IFNA2 9606 - 9:21384254-21385388 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380206 IFNA2-001 21384254-21385388 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonTestisENST00000380206
Transcript ID Brain Colon Testis
ENST00000380206 0.018±0.00 0.040±0.00 0.062±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00056K CIL_00056K_0009 CGP 9:21367424-21385388
CIL_00056K CIL_00056K_0006 CGP 9:21384254-21410185

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005125 IEA cytokine activity
GO:0005126 IEA cytokine receptor binding
GO:0005132 TAS type I interferon receptor binding
GO:0005515 IPI protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006915 TAS apoptotic process
GO:0006952 IEA defense response
GO:0006954 TAS inflammatory response
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007596 TAS blood coagulation
GO:0010629 IDA negative regulation of gene expression
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0042517 IDA positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0045087 TAS innate immune response
GO:0045581 IDA negative regulation of T cell differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046597 IDA negative regulation of viral entry into host cell
GO:0051607 IDA defense response to virus
GO:0060337 TAS type I interferon signaling pathway
GO:0060338 TAS regulation of type I interferon-mediated signaling pathway
GO:2000552 IDA negative regulation of T-helper 2 cell cytokine production
GO:2000663 IDA negative regulation of interleukin-5 secretion
GO:2000666 IDA negative regulation of interleukin-13 secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000063376 Ifna13 interferon alpha 13 protein_coding Mus_musculus
ENSMUSG00000070904 Ifna4 interferon alpha 4 protein_coding Mus_musculus
ENSMUSG00000073811 Ifna12 interferon alpha 12 protein_coding Mus_musculus
ENSMUSG00000078354 Ifna2 interferon alpha 2 protein_coding Mus_musculus
ENSMUSG00000078355 Ifna16 interferon alpha 16 protein_coding Mus_musculus
ENSMUSG00000095270 Ifna9 interferon alpha 9 protein_coding Mus_musculus
ENSMUSG00000095498 Ifna1 interferon alpha 1 protein_coding Mus_musculus
ENSMUSG00000095896 Ifna14 interferon alpha 14 protein_coding Mus_musculus
ENSMUSG00000096011 Ifna15 interferon alpha 15 protein_coding Mus_musculus
ENSMUSG00000096682 Ifna5 interferon alpha 5 protein_coding Mus_musculus
ENSMUSG00000100079 Ifnab interferon alpha B protein_coding Mus_musculus
ENSMUSG00000100549 Ifna11 interferon alpha 11 protein_coding Mus_musculus
ENSMUSG00000100713 Ifna7 interferon alpha 7 protein_coding Mus_musculus
ENSMUSG00000101252 Ifna6 interferon alpha 6 protein_coding Mus_musculus

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