C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: uroporphyrinogen III synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000188690 UROS 9606 - 10:125784980-125823248 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368774 UROS-006 125807150-125823089 protein_coding
  ENST00000368778 UROS-003 125802057-125823196 protein_coding
  ENST00000368786 UROS-002 125788583-125816632 protein_coding
  ENST00000368797 UROS-001 125788578-125823227 protein_coding
  ENST00000420761 UROS-004 125794900-125823248 protein_coding
  ENST00000462490 UROS-007 125791520-125807465 protein_coding
  ENST00000464267 UROS-008 125788725-125798103 processed_transcript
  ENST00000465577 UROS-010 125788587-125798100 processed_transcript
  ENST00000470483 UROS-009 125788577-125795227 processed_transcript
  ENST00000484541 UROS-011 125788582-125796190 processed_transcript
  ENST00000616800 UROS-012 125784980-125796163 protein_coding
  ENST00000622016 UROS-013 125785517-125798119 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368774ENST00000368778ENST00000368797ENST00000420761ENST00000462490
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368774 N/A N/A N/A N/A 2.371±0.00 1.848±0.00 N/A N/A 1.363±0.00 2.324±0.00 N/A N/A N/A N/A
ENST00000368778 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.810±0.00 N/A 1.152±0.00 N/A 3.520±0.20
ENST00000368797 5.624±0.00 9.775±0.00 2.717±0.00 21.208±4.53 11.532±10.68 5.016±3.24 15.659±12.39 12.908±6.82 9.634±8.72 2.937±1.74 7.680±4.69 13.842±7.82 14.333±2.64 18.847±1.98
ENST00000420761 4.891±0.00 7.572±0.00 N/A 24.231±16.55 8.142±6.93 5.449±0.00 8.905±0.00 9.410±0.00 N/A 3.594±0.00 3.202±0.00 6.877±0.00 8.858±0.00 13.715±2.63
ENST00000462490 N/A 2.450±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.499±0.00 0.963±0.00 1.949±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002JY CIL_0002JY_0002 CGP 10:125766453-125823248
CIL_0001V6 CIL_0001V6_0001 CGP 10:125784980-125853695

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004852 IEA uroporphyrinogen-III synthase activity
GO:0005739 ISS mitochondrion
GO:0005829 NAS cytosol
GO:0006778 TAS porphyrin-containing compound metabolic process
GO:0006779 IEA porphyrin-containing compound biosynthetic process
GO:0006780 IDA uroporphyrinogen III biosynthetic process
GO:0006782 IEA protoporphyrinogen IX biosynthetic process
GO:0006783 IC heme biosynthetic process
GO:0033014 IEA tetrapyrrole biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0046677 IEA response to antibiotic
GO:0048037 IEA cofactor binding
GO:0071243 IEA cellular response to arsenic-containing substance
GO:0071418 IEA cellular response to amine stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027491 uros uroporphyrinogen III synthase protein_coding Danio_rerio
ENSMUSG00000030979 Uros uroporphyrinogen III synthase protein_coding Mus_musculus

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