C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: uroporphyrinogen III synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030979 Uros 10090 - 7:133686243-133710072 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033276 Uros-001 133686365-133709281 protein_coding
  ENSMUST00000106144 Uros-005 133692134-133709059 protein_coding
  ENSMUST00000106145 Uros-002 133686356-133709069 protein_coding
  ENSMUST00000106146 Uros-003 133686356-133708958 protein_coding
  ENSMUST00000124759 Uros-007 133701893-133709057 protein_coding
  ENSMUST00000135760 Uros-004 133686243-133709094 retained_intron
  ENSMUST00000144789 Uros-009 133686961-133698080 processed_transcript
  ENSMUST00000151348 Uros-006 133701895-133710072 protein_coding
  ENSMUST00000153698 Uros-008 133701839-133702616 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033276ENSMUST00000106144ENSMUST00000106145ENSMUST00000106146ENSMUST00000135760ENSMUST00000144789ENSMUST00000151348
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033276 2.773±0.75 2.366±0.00 N/A 3.035±1.64 1.846±0.53 1.916±0.46 2.691±0.63 2.621±0.56 3.229±0.95 N/A 3.646±1.33 3.338±1.02 3.804±0.04 1.164±0.13
ENSMUST00000106144 N/A N/A N/A 2.372±0.00 N/A N/A N/A N/A N/A N/A N/A 3.668±0.00 4.631±2.39 1.335±0.00
ENSMUST00000106145 3.710±0.78 8.942±2.01 3.945±0.97 3.125±1.07 4.006±0.64 5.034±1.65 4.498±1.29 7.400±1.46 7.773±4.85 2.979±0.64 3.432±0.96 4.451±1.45 3.898±1.73 2.497±0.25
ENSMUST00000106146 N/A N/A N/A 2.837±0.25 3.052±0.75 N/A N/A N/A 44.495±25.70 N/A 2.047±1.05 3.241±0.71 5.294±3.61 0.561±0.00
ENSMUST00000135760 4.327±1.35 N/A 6.360±2.98 6.174±3.35 6.285±0.61 2.832±1.81 1.263±0.00 3.185±0.30 16.872±12.37 2.723±1.15 1.025±0.22 4.609±1.43 3.987±0.99 1.604±0.06
ENSMUST00000144789 N/A N/A N/A N/A 9.779±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000151348 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.885±6.22 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002JY CIL_0002JY_0003 CGP 7:133674270-133710072
CIL_0001V6 CIL_0001V6_0002 CGP 7:133686243-133721145

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004852 IDA uroporphyrinogen-III synthase activity
GO:0005739 IDA mitochondrion
GO:0005829 IEA cytosol
GO:0006779 IDA porphyrin-containing compound biosynthetic process
GO:0006780 IEA uroporphyrinogen III biosynthetic process
GO:0006782 IEA protoporphyrinogen IX biosynthetic process
GO:0046677 IEA response to antibiotic
GO:0048037 IEA cofactor binding
GO:0071243 IEA cellular response to arsenic-containing substance
GO:0071418 IEA cellular response to amine stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027491 uros uroporphyrinogen III synthase protein_coding Danio_rerio
ENSG00000188690 UROS uroporphyrinogen III synthase protein_coding Homo_sapiens

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