C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196296 ATP2A1 9606 + 16:28878405-28904509 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357084 ATP2A1-001 28878405-28904464 protein_coding
  ENST00000395503 ATP2A1-002 28878488-28904509 protein_coding
  ENST00000536376 ATP2A1-003 28880053-28904464 protein_coding
  ENST00000562185 ATP2A1-008 28879243-28882580 protein_coding
  ENST00000563975 ATP2A1-007 28878861-28882551 protein_coding
  ENST00000564112 ATP2A1-010 28903373-28903826 protein_coding
  ENST00000564470 ATP2A1-005 28888897-28894219 nonsense_mediated_decay
  ENST00000564732 ATP2A1-009 28887663-28900618 nonsense_mediated_decay
  ENST00000565042 ATP2A1-006 28888897-28894219 processed_transcript

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastKidneyLiverMuscleTestisENST00000357084ENST00000395503ENST00000536376
Transcript ID Brain Breast Kidney Liver Muscle Testis
ENST00000357084 0.727±0.00 N/A N/A 1.295±0.00 N/A 2.952±0.00
ENST00000395503 N/A 124.548±0.00 N/A 0.334±0.00 328.223±54.89 N/A
ENST00000536376 N/A 43.326±0.00 0.021±0.00 N/A 51.441±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0005388 IDA:IEA calcium-transporting ATPase activity
GO:0005509 ISS calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005793 ISS endoplasmic reticulum-Golgi intermediate compartment
GO:0006200 ISS ATP catabolic process
GO:0006816 IDA:IEA calcium ion transport
GO:0006942 IMP regulation of striated muscle contraction
GO:0007596 TAS blood coagulation
GO:0008152 IEA metabolic process
GO:0008637 IMP apoptotic mitochondrial changes
GO:0016020 ISS membrane
GO:0016021 NAS:IEA integral component of membrane
GO:0016529 ISS sarcoplasmic reticulum
GO:0031095 TAS platelet dense tubular network membrane
GO:0031448 IDA positive regulation of fast-twitch skeletal muscle fiber contraction
GO:0031673 IDA H zone
GO:0031674 IDA I band
GO:0032470 IMP positive regulation of endoplasmic reticulum calcium ion concentration
GO:0032471 IMP negative regulation of endoplasmic reticulum calcium ion concentration
GO:0033017 TAS sarcoplasmic reticulum membrane
GO:0034220 TAS ion transmembrane transport
GO:0034704 IC calcium channel complex
GO:0034976 IMP response to endoplasmic reticulum stress
GO:0042803 IPI protein homodimerization activity
GO:0045988 IMP negative regulation of striated muscle contraction
GO:0046872 IEA metal ion binding
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051561 IMP positive regulation of mitochondrial calcium ion concentration
GO:0051659 IMP maintenance of mitochondrion location
GO:0055085 TAS transmembrane transport
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070509 IMP calcium ion import
GO:0070588 IEA calcium ion transmembrane transport
GO:0090076 IDA relaxation of skeletal muscle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020574 atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 protein_coding Danio_rerio
ENSDARG00000035458 atp2a1l ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like protein_coding Danio_rerio
ENSMUSG00000030730 Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 protein_coding Mus_musculus

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