C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000395503 ATP2A1-002 ENSG00000196296 9606 + 16:28878488-28904509 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastLiverMuscleENST00000395503
Transcript ID Breast Liver Muscle
ENST00000395503 124.548±0.00 0.334±0.00 328.223±54.89

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0005388 IDA:IEA calcium-transporting ATPase activity
GO:0005509 ISS calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005793 ISS endoplasmic reticulum-Golgi intermediate compartment
GO:0006200 ISS ATP catabolic process
GO:0006816 IDA:IEA calcium ion transport
GO:0006942 IMP regulation of striated muscle contraction
GO:0007596 TAS blood coagulation
GO:0008152 IEA metabolic process
GO:0008637 IMP apoptotic mitochondrial changes
GO:0016020 ISS membrane
GO:0016021 NAS:IEA integral component of membrane
GO:0016529 ISS sarcoplasmic reticulum
GO:0031095 TAS platelet dense tubular network membrane
GO:0031448 IDA positive regulation of fast-twitch skeletal muscle fiber contraction
GO:0031673 IDA H zone
GO:0031674 IDA I band
GO:0032470 IMP positive regulation of endoplasmic reticulum calcium ion concentration
GO:0032471 IMP negative regulation of endoplasmic reticulum calcium ion concentration
GO:0033017 TAS sarcoplasmic reticulum membrane
GO:0034220 TAS ion transmembrane transport
GO:0034704 IC calcium channel complex
GO:0034976 IMP response to endoplasmic reticulum stress
GO:0042803 IPI protein homodimerization activity
GO:0045988 IMP negative regulation of striated muscle contraction
GO:0046872 IEA metal ion binding
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051561 IMP positive regulation of mitochondrial calcium ion concentration
GO:0051659 IMP maintenance of mitochondrion location
GO:0055085 TAS transmembrane transport
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070509 IMP calcium ion import
GO:0070588 IEA calcium ion transmembrane transport
GO:0090076 IDA relaxation of skeletal muscle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000032974 Atp2a1-001 protein_coding Mus_musculus 0 4098
ENSDART00000043932 atp2a1-001 protein_coding Danio_rerio 0 1943
ENSDART00000129561 atp2a1-002 protein_coding Danio_rerio 0 1943
ENSDART00000146241 atp2a2a-003 protein_coding Danio_rerio 0 1906
ENSDART00000042040 atp2a2a-001 protein_coding Danio_rerio 0 1906
ENSMUST00000021142 Atp2a3-201 protein_coding Mus_musculus 0 1445
ENSMUST00000108485 Atp2a3-202 protein_coding Mus_musculus 0 1445
ENSMUST00000163326 Atp2a3-203 protein_coding Mus_musculus 0 1445
ENSMUST00000031423 Atp2a2-201 protein_coding Mus_musculus 0 1435
ENSMUST00000177974 Atp2a2-202 protein_coding Mus_musculus 0 1435
ENSMUST00000179939 Atp2a2-203 protein_coding Mus_musculus 0 1435
ENSMUST00000108484 Atp2a3-002 protein_coding Mus_musculus 0 592
ENSMUST00000108486 Atp2a3-001 protein_coding Mus_musculus 0 592
ENSMUST00000146973 Atp2a1-003 protein_coding Mus_musculus 0 532
ENSMUST00000133300 Rabep2-009 processed_transcript Mus_musculus 0 420
ENSMUST00000126363 Atp2a1-002 processed_transcript Mus_musculus 0 292

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