C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030730 Atp2a1 10090 - 7:126445858-126463108 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032974 Atp2a1-001 126445858-126463108 protein_coding
  ENSMUST00000126363 Atp2a1-002 126462494-126463108 processed_transcript
  ENSMUST00000146973 Atp2a1-003 126445860-126447645 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartKidneyLiverLungMusclePlacentaENSMUST00000032974ENSMUST00000146973
Transcript ID Breast Heart Kidney Liver Lung Muscle Placenta
ENSMUST00000032974 1102.983±258.54 1.086±0.36 38.458±1.00 0.797±0.00 21.915±19.61 7450.746±352.77 0.681±0.00
ENSMUST00000146973 995.053±428.57 N/A N/A N/A 72.767±6.30 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000557 CIL_000557_0002 CGP 7:126428759-126463108

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005388 ISS calcium-transporting ATPase activity
GO:0005509 ISS calcium ion binding
GO:0005515 IEA protein binding
GO:0005524 ISS ATP binding
GO:0005783 ISS endoplasmic reticulum
GO:0005789 ISS endoplasmic reticulum membrane
GO:0005793 ISS endoplasmic reticulum-Golgi intermediate compartment
GO:0006200 ISS ATP catabolic process
GO:0006816 ISS calcium ion transport
GO:0006937 TAS regulation of muscle contraction
GO:0006942 ISS regulation of striated muscle contraction
GO:0008637 IEA apoptotic mitochondrial changes
GO:0016020 ISS membrane
GO:0016021 IEA integral component of membrane
GO:0016529 ISS sarcoplasmic reticulum
GO:0031448 ISS positive regulation of fast-twitch skeletal muscle fiber contraction
GO:0031673 ISS H zone
GO:0031674 ISS I band
GO:0032470 IEA positive regulation of endoplasmic reticulum calcium ion concentration
GO:0032471 IEA negative regulation of endoplasmic reticulum calcium ion concentration
GO:0034976 IEA response to endoplasmic reticulum stress
GO:0042803 IEA protein homodimerization activity
GO:0045988 ISS negative regulation of striated muscle contraction
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051561 IEA positive regulation of mitochondrial calcium ion concentration
GO:0051659 IEA maintenance of mitochondrion location
GO:0070059 IEA intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070509 IEA calcium ion import
GO:0090076 IEA relaxation of skeletal muscle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020574 atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 protein_coding Danio_rerio
ENSDARG00000035458 atp2a1l ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like protein_coding Danio_rerio
ENSG00000196296 ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 protein_coding Homo_sapiens

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