C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 22 (organic cation/zwitterion transporter), member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197208 SLC22A4 9606 + 5:132294443-132344206 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000200652 SLC22A4-001 132294443-132344206 protein_coding
  ENST00000425923 SLC22A4-002 132322184-132327385 processed_transcript
  ENST00000491257 SLC22A4-003 132295425-132320972 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLungOvaryPlacentaENST00000200652
Transcript ID Brain Heart Lung Ovary Placenta
ENST00000200652 1.916±0.00 0.641±0.00 4.654±0.00 2.834±1.79 1.149±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093D CIL_00093D_0001 VISTA 5:131965137-132566411
CIL_0007RF CIL_0007RF_0001 VISTA 5:131967147-132570227
CIL_0000HR CIL_0000HR_0002 CGP 5:132294443-132395614

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 TAS nucleotide binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005886 IC plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006641 IEA triglyceride metabolic process
GO:0006814 IEA sodium ion transport
GO:0007589 TAS body fluid secretion
GO:0008513 TAS secondary active organic cation transmembrane transporter activity
GO:0009437 IEA carnitine metabolic process
GO:0015075 IEA ion transmembrane transporter activity
GO:0015226 IDA carnitine transmembrane transporter activity
GO:0015293 IEA symporter activity
GO:0015491 IDA cation:cation antiporter activity
GO:0015651 IDA quaternary ammonium group transmembrane transporter activity
GO:0015695 TAS organic cation transport
GO:0015697 IDA quaternary ammonium group transport
GO:0015879 IDA carnitine transport
GO:0016021 IEA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0022857 IEA transmembrane transporter activity
GO:0030165 IPI PDZ domain binding
GO:0034220 IEA ion transmembrane transport
GO:0055085 TAS:IEA transmembrane transport
GO:0098655 IDA cation transmembrane transport
GO:1902603 IDA carnitine transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005335 slc22a4 solute carrier family 22 (organic cation/ergothioneine transporter), member 4 protein_coding Danio_rerio
ENSDARG00000068603 slc22a5 solute carrier family 22 (organic cation/carnitine transporter), member 5 protein_coding Danio_rerio
ENSDARG00000094112 slc22a21 solute carrier family 22 (organic cation transporter), member 21 protein_coding Danio_rerio
ENSMUSG00000020334 Slc22a4 solute carrier family 22 (organic cation transporter), member 4 protein_coding Mus_musculus

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