C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 27
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197272 IL27 9606 - 16:28499362-28512051 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356897 IL27-001 28499362-28506834 protein_coding
  ENST00000568075 IL27-002 28501974-28512051 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000356897ENST00000568075
Transcript ID Adrenal Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000356897 0.103±0.00 0.059±0.00 0.052±0.00 0.105±0.00 0.093±0.00 0.793±0.00 0.307±0.00 N/A 0.535±0.00 0.109±0.02
ENST00000568075 0.084±0.00 N/A N/A 0.080±0.00 0.873±0.63 N/A N/A 0.143±0.00 0.381±0.00 0.141±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005TV CIL_0005TV_0001 CGP 16:28494649-28512051
CIL_0005TU CIL_0005TU_0001 CGP 16:28499362-28539174

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005102 ISS receptor binding
GO:0005125 IEA cytokine activity
GO:0005515 IEA protein binding
GO:0005615 ISS extracellular space
GO:0006954 IEA inflammatory response
GO:0009617 IEA response to bacterium
GO:0042129 ISS regulation of T cell proliferation
GO:0045078 IDA positive regulation of interferon-gamma biosynthetic process
GO:0045087 IEA innate immune response
GO:0045523 ISS interleukin-27 receptor binding
GO:0045625 IDA regulation of T-helper 1 cell differentiation
GO:0050688 IEA regulation of defense response to virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000044701 Il27 interleukin 27 protein_coding Mus_musculus

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