C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: deiodinase, iodothyronine, type III
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197406 DIO3 9606 + 14:101561351-101563452 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000510508 DIO3-001 101561351-101563452 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000510508
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000510508 2.628±0.00 2.467±0.00 0.265±0.13 0.131±0.10 1.331±1.11 0.290±0.00 1.095±0.00 0.061±0.02 1.428±0.00 1.028±0.68 5.568±7.02 19.308±11.30 2.624±2.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004AB CIL_0004AB_0001 CGP 14:100880655-101563452
CIL_0004A7 CIL_0004A7_0001 CGP 14:101561351-101927989

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004800 NAS:IEA thyroxine 5'-deiodinase activity
GO:0005768 IEA endosome
GO:0005886 TAS plasma membrane
GO:0006590 TAS thyroid hormone generation
GO:0008150 ND biological_process
GO:0016021 IEA integral component of membrane
GO:0033798 IEA thyroxine 5-deiodinase activity
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0040018 IEA positive regulation of multicellular organism growth
GO:0042404 IEA thyroid hormone catabolic process
GO:0042446 IEA hormone biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089937 dio3a deiodinase, iodothyronine, type IIIa protein_coding Danio_rerio
ENSMUSG00000075707 Dio3 deiodinase, iodothyronine type III protein_coding Mus_musculus

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