C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: matrix metallopeptidase 17 (membrane-inserted)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198598 MMP17 9606 + 12:131828393-131851783 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360564 MMP17-001 131828393-131851771 protein_coding
  ENST00000534865 MMP17-005 131840025-131849981 protein_coding
  ENST00000535004 MMP17-010 131845295-131851367 protein_coding
  ENST00000535182 MMP17-012 131840736-131845391 processed_transcript
  ENST00000535271 MMP17-011 131849835-131851332 retained_intron
  ENST00000535291 MMP17-002 131838056-131851783 protein_coding
  ENST00000537848 MMP17-007 131844870-131851030 nonsense_mediated_decay
  ENST00000542142 MMP17-006 131841768-131844721 retained_intron
  ENST00000542648 MMP17-008 131844961-131850062 protein_coding
  ENST00000545671 MMP17-003 131828406-131841736 protein_coding
  ENST00000545790 MMP17-004 131828540-131840747 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360564ENST00000534865ENST00000535004ENST00000535182ENST00000535271ENST00000535291ENST00000537848ENST00000542142ENST00000542648ENST00000545671ENST00000545790
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360564 0.693±0.00 0.433±0.00 6.434±0.00 1.597±1.44 0.688±0.00 0.123±0.00 0.161±0.00 0.054±0.00 1.039±0.00 0.072±0.00 4.006±3.89 0.390±0.00 1.154±0.92
ENST00000534865 N/A N/A N/A N/A N/A N/A N/A 0.147±0.08 N/A 0.070±0.00 N/A N/A 0.228±0.00
ENST00000535004 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.444±0.00 1.046±0.00 1.231±0.00
ENST00000535182 N/A N/A N/A N/A N/A 0.107±0.00 N/A N/A 0.778±0.00 N/A N/A 0.743±0.03 N/A
ENST00000535271 N/A 0.859±0.00 N/A N/A N/A N/A 0.274±0.00 0.873±0.00 N/A N/A N/A N/A N/A
ENST00000535291 N/A N/A 2.477±0.00 0.736±0.00 N/A N/A N/A N/A N/A N/A 0.214±0.00 N/A 0.378±0.00
ENST00000537848 N/A N/A 2.476±0.00 N/A N/A N/A N/A 0.754±0.00 N/A N/A 0.848±0.00 0.416±0.00 N/A
ENST00000542142 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.062±0.00 N/A N/A N/A
ENST00000542648 0.579±0.00 N/A N/A N/A 0.564±0.46 N/A N/A N/A N/A 0.248±0.00 0.593±0.00 0.551±0.00 0.654±0.00
ENST00000545671 N/A N/A N/A N/A N/A 0.286±0.15 1.021±0.00 N/A 0.251±0.00 N/A N/A N/A N/A
ENST00000545790 N/A N/A N/A 0.756±0.00 0.232±0.00 N/A 0.270±0.00 0.099±0.00 N/A N/A N/A 0.281±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00042X CIL_00042X_0001 CGP 12:131711081-131851783

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005887 TAS integral component of plasma membrane
GO:0006508 IEA proteolysis
GO:0008047 TAS enzyme activator activity
GO:0008237 IEA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0031012 IEA extracellular matrix
GO:0031225 IEA anchored component of membrane
GO:0043085 TAS positive regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078915 mmp17a matrix metallopeptidase 17a protein_coding Danio_rerio
ENSMUSG00000029436 Mmp17 matrix metallopeptidase 17 protein_coding Mus_musculus

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