C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDC42 binding protein kinase beta (DMPK-like)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198752 CDC42BPB 9606 - 14:102932379-103057462 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361246 CDC42BPB-001 102932379-103057462 protein_coding
  ENST00000558321 CDC42BPB-006 102986298-103004023 retained_intron
  ENST00000558867 CDC42BPB-004 102944011-102945331 protein_coding
  ENST00000559043 CDC42BPB-002 102944043-102968532 protein_coding
  ENST00000559245 CDC42BPB-007 102943813-102945724 retained_intron
  ENST00000559790 CDC42BPB-008 102939916-102940726 retained_intron
  ENST00000560492 CDC42BPB-005 102939908-102940747 retained_intron
  ENST00000561271 CDC42BPB-003 102986510-103004279 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000361246
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000361246 23.766±0.00 6.392±0.00 2.887±0.00 14.857±11.27 19.952±0.00 20.083±0.00 7.379±6.41 1.016±0.00 3.707±0.00 3.124±2.47 9.043±6.97 15.132±2.75 19.248±0.73

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AG CIL_0009AG_0001 VISTA 14:102447254-103047442
CIL_00040T CIL_00040T_0001 CGP 14:102777476-102933596
CIL_0001GW CIL_0001GW_0001 CGP 14:102922656-103057462

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0004672 IDA:IEA protein kinase activity
GO:0004674 ISS:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IEA protein binding
GO:0005524 ISS:IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005856 TAS cytoskeleton
GO:0005886 IEA plasma membrane
GO:0005911 ISS cell-cell junction
GO:0006468 ISS:IEA protein phosphorylation
GO:0007010 TAS cytoskeleton organization
GO:0007163 TAS establishment or maintenance of cell polarity
GO:0007165 TAS signal transduction
GO:0016477 IMP cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017048 IEA Rho GTPase binding
GO:0030036 IEA actin cytoskeleton organization
GO:0031032 IMP actomyosin structure organization
GO:0031252 ISS cell leading edge
GO:0031532 ISS actin cytoskeleton reorganization
GO:0035556 IEA intracellular signal transduction
GO:0042641 IDA actomyosin
GO:0050790 IEA regulation of catalytic activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019383 cdc42bpb CDC42 binding protein kinase beta (DMPK-like) protein_coding Danio_rerio
ENSMUSG00000021279 Cdc42bpb CDC42 binding protein kinase beta protein_coding Mus_musculus

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