C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class I, E
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204592 HLA-E 9606 + 6:30489406-30494205 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376630 HLA-E-001 30489467-30494205 protein_coding
  ENST00000484194 HLA-E-002 30489510-30490365 retained_intron
  ENST00000493699 HLA-E-003 30489512-30491283 retained_intron
  ENST00000612468 HLA-E-201 30489406-30494204 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376630ENST00000493699
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376630 694.468±0.00 379.523±0.00 12.843±0.00 57.533±47.21 184.080±125.07 162.077±127.13 53.174±33.64 118.233±74.19 77.201±33.16 1000.711±896.71 44.881±32.38 149.384±69.25 433.421±155.14 88.583±57.59
ENST00000493699 N/A N/A 55.396±0.00 15.481±0.00 170.940±0.00 151.164±0.00 28.188±0.00 89.907±0.00 92.083±0.00 142.168±0.00 28.880±0.00 65.725±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 IEA antigen processing and presentation of peptide antigen via MHC class I
GO:0005515 IEA protein binding
GO:0006955 IEA immune response
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019882 IEA antigen processing and presentation
GO:0042605 IEA peptide antigen binding
GO:0042612 IEA MHC class I protein complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000037334 H2-M1 histocompatibility 2, M region locus 1 protein_coding Mus_musculus
ENSMUSG00000037537 H2-M11 histocompatibility 2, M region locus 11 protein_coding Mus_musculus
ENSMUSG00000067201 H2-M9 histocompatibility 2, M region locus 9 protein_coding Mus_musculus

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